[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538113":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":53,"collaborators":56,"id":69,"slug":25,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":25,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":25,"enrollmentInfo":78,"targetDuration":25,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":90,"whyStopped":25,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Università degli Studi di Sassari","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"A-oss and autogenous bone","EXPERIMENTAL","In these group a GBR will be performed using only A-oss and autologous bone will be added and then will be covered with a membrane.",[13],"Procedure: A-oss and autogenous bone",{"label":15,"type":16,"description":17,"interventionNames":18},"A-oss and LCR-A","ACTIVE_COMPARATOR","In these subjects a GBR will be performed using only A-oss and LCR-A and then will be covered with a membrane.",[19],"Procedure: A-oss an LCR-A",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Horizontal ridge augmentation in one stages approach will be performed using a mix of A-Oss and autologenous bone.",[9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"A-oss an LCR-A","Horizontal ridge augmentation in one stages approach will be performed using OssMem with A-Oss and LCR-A",[15],[31],{"facility":32,"status":25,"city":33,"state":25,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Marco Tallarico","Sassari","07100","Italy","IT",{"type":38,"coordinates":39},"Point",[40,41],8.55552,40.72586,{"lat":41,"lon":40},[44,49],{"name":45,"role":46,"phone":47,"phoneExt":25,"email":48},"Dario Melodia, Dr","CONTACT","3331226618","dariomld1@gmail.com",{"name":50,"role":46,"phone":51,"phoneExt":25,"email":52},"Marco Tallarico, Prof","3280758769","me@studiomarcotallarico.it",{"type":54,"investigatorFullName":32,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Aisstent Professor",[57,60,62,65,67],{"name":58,"class":59},"Melodia, Dario, M.D.","INDIV",{"name":61,"class":59},"Pisano, Milena, M.D.",{"name":63,"class":64},"Dr. Aurea Lumbau","UNKNOWN",{"name":66,"class":59},"Meloni, Silvio Mario, M.D.",{"name":68,"class":59},"Baldoni, Edoardo, M.D.","100538113",false,"NCT06286605","RCT GBR One Stages Comparing A-Oss and Autogenous Bone Versus A-Oss and LCR-A","Horizontal Ridge Augmentation Using One-stage Guided Bone Regeneration (GBR) for Bone Defect Class IV of Cawed and Howell With Collagene Membrane (OssMem) and a Mix of Bovine Bone Substitute (A-Oss) and Autogenous Bone Versus A-Oss and LCR-A, a Synthetic Bone : a Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients that required an implant supported restoration and staged horizontal guided bone regeneration (defect of class IV according to Cawed and Howell) in both mandible or maxilla.\n* Patents able to understand and sign an informed consent.\n* Patients were to be 18 years or older with a residual horizontal ridge thickness of 4 mm or less (Cawood-Howell Class III- IV) in the intended implant site.\n* Smokers will be categorized into: 1) non smokers; 2) moderate smokers (smoking up to 10 cigarettes\u002Fday); 3) heavy smokers (smoking more than 11 cigarettes\u002Fday). Only categories 1 and 2 will be included.\n\nExclusion Criteria:\n\n* General contraindications to implant surgery.\n* Patients irradiated in the head and neck area.\n* Immunosuppressed or immunocompromised patients.\n* Patients treated or under treatment with intravenous amino-bisphosphonates.\n* Patients with untreated periodontitis.\n* Patients with poor oral hygiene and motivation.\n* Uncontrolled diabetes.\n* Pregnancy or nursing.\n* Substance abuser.\n* Heavy smokers (smoking more than 11 cigarettes\u002Fday).\n* Psychiatric problems or unrealistic expectations.\n* Lack of opposite occluding dentition in the area intended for implant placement.\n* Immediate implants (extractive sites will have to be healed from 6-8 weeks).\n* Patients participating in other studies, if the present protocol cannot be properly adhered to.\n* Patients referred only for implant placement and cannot be followed ant the treating centre.\n* Patients unable to be followed for 5 years",true,"ALL","18 Years",{"count":79,"type":80},42,"ESTIMATED","INTERVENTIONAL",[83],"NA","The aim of this randomized controlled trial is to evaluate the tridimensional bone stability after horizontal one-stage GBR using collagene membrane (OssMem) with a mix of Bovine Bone Substitute (A-Oss) and autogenous bone (test group) versus A-Oss and LCR-A, a synthetic bone (control group).",[86,87],"Guided Bone Regeneration","Dental Implant",[87,89],"GBR","NOT_YET_RECRUITING","2024-02-21",{"date":93,"type":94},"2024-02-29","ACTUAL",{"date":96,"type":80},"2024-03-01",{"date":98,"type":80},"2028-12-30",{"name":5,"class":6},1]