RecistTM Criteria in Evaluating the Efficacy of Targeted Therapy for NSCLC

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorXueqin Yang

About this trial

Investigators established the efficacy evaluation criteria for tumor markers (RecistTM) in the preliminary research. Among patients with advanced non-small cell lung cancer, patients with positive driving genes are more likely to exhibit abnormalities in tumor markers, which suggests that this criteria may be more suitable for evaluating the efficacy of targeted therapy in driving gene positive patients. Moreover, The judgment rules of the prelimary criteria still need further improvement. Therefore, in order to broaden the application scope of the RecistTM criteria, further improve the evaluation rules of RecistTM criteria, and multi-dimensionally confirm the reliability of RecistTM criteria on efficacy evaluation, investigators plan to conduct research on the application of RecistTM criteria in evaluating the efficacy of targeted therapy for advanced non-small cell lung cancer with positive driving genes.

Eligibility criteria

Qualifiers

NSCLC patients with stage IIIB-IV

Driver gene positive (EGFR,ALK,C-MET, ROS,RET, HER2);

First line targeted therapy.

Performance status of 0-2 on the ECOG criteria.

Disqualifiers

Patients with dysphagia;

Unable to taking medication on time;

Patients with a history of abuse of psychotropic substances who are unable to quit or have mental disorders

Trial design

Treatments tested in this trial

  • RecistTM criteria

Treatment groups

No treatment groups listed

Sponsors and collaborators

Xueqin Yang

Lead sponsor

Third Military Medical University

Sponsor institution