Rehabilitating Vision Loss in Veterans With Age-Related Macular Degeneration

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age50+

SponsorVA Office of Research and Development

About this trial

This study will help develop new methods of rehabilitating Veterans with vision loss due to Age-related macular degeneration.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

The subject is a Veteran.

The subject is 50 years of age.

The subject has best-corrected visual acuity (BCVA) of 20/40 or worse in each eye, as determined by the standard CNVAMC optometric tests.

The subject has visual field deficit of 10O in either eye as determined by the Octopus 900 perimetry (Haag-Streit Diagnostics, Haag-Streit USA, Mason, OH) administered by CNVAMC. (When the deficit/s are binocular, they do not necessarily have to be in binocularly corresponding positions.)

Disqualifiers

According to the patient's VA clinical records, the patient has one or more clinically diagnosed neurological disorder.

According to the patient's VA clinical records, the patient has one or more clinically diagnosed cognitive deficits.

According to the patient's VA clinical records, the patient has been clinically diagnosed with a psychiatric disorder that would make it unduly uncomfortable or otherwise clinically inadvisable for the subject to participate in the study.

According to the patient's VA clinical records, according to the patient, or both, the patient has motor disorder/s that would make it unduly uncomfortable or otherwise clinically inadvisable for the subject to participate in the study.

Trial population

Veterans with vision loss caused by age-related macular degeneratioin

Trial design

Design model

Case-control

Time perspective

Prospective

Treatments tested in this trial

Study-specific rehabilitation (SSR) procedures
Behavioral
Study-specific rehabilitation procedures will systematically manipulated the spatial or temporal synchrony (or coordination) of visual vs. haptic inputs that the subjects receive.

Treatment groups

20 Participants

are divided into 2 treatment groups

Group A: Treatment Group1 intervention

Group B: Control Group0 interventions

Trial outcomes

Primary outcomes

Accuracy of object recognition

This outcome will be measured as the accuracy (% correct) with which the study subjects recognize the text objects before, during and after their participation in the study procedures.

Time frame

6-10 weeks

Response of brain regions of interest (ROI) as reflected in the BOLD (blood oxygenation level-dependent) response

This outcome will be measured as changes (if any) of the BOLD responses of brain ROIs before, during and after their participation in the study procedures.

Time frame

6-10 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

VA Office of Research and Development

Lead sponsor

Augusta University

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: