Remote Intervention to Prevent Overdose

ConditionAccidental Overdose of Opiate

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorUniversity of Alabama at Birmingham

About this trial

This Type 1 hybrid effectiveness-implementation randomized controlled trial, Remote Fentanyl Test Strip Distribution and Education to Prevent Drug Overdose, aims to address the United States opioid crisis driven by fentanyl and other synthetic opioids by reducing overdose rates. It is supported by and included in the HEAL Initiative. This study would be the first national, fully remote trial to assess the impact of fentanyl test strips on overdose outcomes, using a novel 2x2 design crossing fentanyl test strip distribution and education to determine which approach most significantly reduces overdose rates while minimizing costs. This research will inform scalability around mail-based fentanyl test strip distribution and education programs to address the nation's opioid overdose crisis.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

18 years old

English-speaking and reading

Report using illicit opioids and/or stimulants (including counterfeit pills) within the past 3 months per the ASSIST

Able and willing to provide informed consent

Disqualifiers

Living in a restricted environment (e.g., prison)

Trial design

Design model

Factorial

Treatments tested in this trial

Fentanyl test strips
Other intervention
Fentanyl test strips (FTS) are small strips of paper that can detect the presence of fentanyl in illicit drugs.
Fentanyl test strip education
Behavioral
Developed in the R61 phase, the educational intervention will provide participants with knowledge about how to correctly use fentanyl strips.

Treatment groups

100 Participants

are divided into 4 treatment groups

Group A: FDEExperimental treatment 2 interventions

Group B: EExperimental treatment 1 intervention

Group C: FDExperimental treatment 1 intervention

Group D: RNo intervention 0 interventions

Trial outcomes

Primary outcomes

Overdose

Includes both self-reported non-fatal overdose and fatal overdose

Time frame

Baseline, 1 month, 3 months, 6 months

Secondary outcomes

Fentanyl test strip knowledge

Self-reported knowledge of how and when to use fentanyl test strips correctly, based on the fentanyl test strip education intervention developed in R61 phase

Time frame

Baseline, 1 month, 3 months, 6 months

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Alabama at Birmingham

Lead sponsor

National Institute on Drug Abuse (NIDA)

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: