[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619488":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":23,"locations":33,"responsibleParty":98,"collaborators":100,"id":108,"slug":10,"hasResults":109,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":109,"sex":114,"minAge":115,"maxAge":10,"enrollmentInfo":116,"targetDuration":10,"studyType":119,"phases":10,"briefSummary":120,"conditions":121,"keywords":123,"overallStatus":127,"whyStopped":10,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":137},{"fullName":5,"class":6},"Imperial College London","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TNM5",null,"Patients with rectal cancer diagnosed between 2007-2017 who were staged using TNM5",[13],"Other: No Intervention: Observational Cohort",{"label":15,"type":10,"description":16,"interventionNames":17},"TNM8","Patients with rectal cancer diagnosed between 2022-2024 who were staged using TNM8",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"No Intervention: Observational Cohort","No intervention is to be performed. This is an observational retrospective cohort study only",[9,15],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Gina Brown","CONTACT","07917302097","gina.brown@imperial.ac.uk",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Harpreet Sekhon","07923595222","hks224@ic.ac.uk",[34,54,69,84],{"facility":35,"status":10,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Croydon Health Services NHS Trusts","Croydon","Select Your County","CR7 7YE","United Kingdom","UK",{"type":42,"coordinates":43},"Point",[44,45],-0.1,51.38333,{"lat":45,"lon":44},[48,52],{"name":49,"role":26,"phone":50,"phoneExt":10,"email":51},"Annabel Shaw","07708925886","annabel.shaw@nhs.net",{"name":49,"role":53,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"facility":55,"status":10,"city":56,"state":37,"zip":57,"country":39,"countryCode":40,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"London North West University Healthcare NHS Trust","London","NW10 7NS",{"type":42,"coordinates":59},[60,61],-0.12574,51.50853,{"lat":61,"lon":60},[64,68],{"name":65,"role":26,"phone":66,"phoneExt":10,"email":67},"Nicola Hodges","07702088521","nicola.hodges@nhs.net",{"name":65,"role":53,"phone":10,"phoneExt":10,"email":10},{"facility":70,"status":10,"city":71,"state":10,"zip":72,"country":39,"countryCode":40,"cosmosGeoPoint":73,"geoPoint":77,"contacts":78},"Basingstoke and North Hampshire Hospital","Basingstoke","RG24 9NA",{"type":42,"coordinates":74},[75,76],-1.08708,51.26249,{"lat":76,"lon":75},[79,83],{"name":80,"role":26,"phone":81,"phoneExt":10,"email":82},"Amy Lord","07841590064","amycharlottelord@gmail.com",{"name":80,"role":53,"phone":10,"phoneExt":10,"email":10},{"facility":85,"status":10,"city":86,"state":10,"zip":87,"country":39,"countryCode":40,"cosmosGeoPoint":88,"geoPoint":92,"contacts":93},"Epsom and St Helier University Hospitals NHS Trust","Surrey Quays","SM5 1AA",{"type":42,"coordinates":89},[90,91],-0.04802,51.49353,{"lat":91,"lon":90},[94,97],{"name":95,"role":26,"phone":10,"phoneExt":10,"email":96},"Tou Pin Chang","toupin.chang@nhs.net",{"name":95,"role":53,"phone":10,"phoneExt":10,"email":10},{"type":99,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[101,103,104,106],{"name":102,"class":6},"Croydon Health Services NHS Trust",{"name":85,"class":6},{"name":70,"class":105},"UNKNOWN",{"name":107,"class":105},"London North West University Health Care NHS Trust","100619488",false,"NCT07345273","Reporting of Tumour Deposits in Colorectal Cancer by Radiology and Pathology","RADAR","Inclusion Criteria:\n\n1. Primary adenocarcinoma of the rectum (proven by biopsy)\n2. Undergone surgical resection between 01st January 2007 to 31st December 2017 inclusive for the TNM 5 cohort\n3. Undergone surgical resection between 01st January 2022 to 31st December 2024 inclusive for the TNM 8 cohort\n\n3\\. Staging with MRI reports are available 4. Post-operative pathology report available 5. Patients aged 16 years and over\n\nExclusion Criteria:\n\n1. Synchronous metastatic tumours\n2. Under the age of 16 years\n3. MRI and\u002For pathology reports are not available","ALL","16 Years",{"count":117,"type":118},225,"ESTIMATED","OBSERVATIONAL","Recent research shows that tumour deposits-small spots of cancer found near the main bowel tumour-may give doctors important information about how aggressive the cancer is and how likely it is to come back.\n\nDoctors can find tumour deposits either:\n\n1. When looking at scans before surgery, or\n2. when examining the removed bowel tissue under the microscope after surgery.\n\nIn the past, tumour deposits were not always recorded properly. This is because older cancer-staging systems (called TNM 5) used in the UK treated these spots differently, depending on their size, and sometimes labelled them as lymph nodes even when they were not. As a result, many tumour deposits were missed in reports.\n\nSince 2018, the UK has been using an updated staging system (called TNM 8) that gives tumour deposits their own category. This means doctors are now expected to report them separately when they are found in the tissue around the bowel.\n\nThis matters because the investigators know that patients who have tumour deposits may have a higher risk of the cancer returning or spreading. Because of this, these patients might benefit from extra treatment-such as chemotherapy or radiotherapy-on top of surgery.\n\nHowever, if tumour deposits are not routinely recorded on scans or pathology reports, doctors may not realise a patient has them. This means that:\n\n1. Patients may not get the most appropriate advice about their cancer, and\n2. Patients may miss out on treatments that could help reduce the chance of the cancer returning.\n\nThis research project aims to find out two things:\n\n1. Are tumour deposits being routinely reported on scans and pathology reports for rectal cancer since the newer TNM 8 system was introduced? And\n2. Is there a link between reporting tumour deposits and another important finding called EMVI (extramural vascular invasion), which also affects cancer behaviour and treatment decisions?",[122],"Rectal Adenocarcinoma",[122,124,125,126],"Tumour Deposits","TNM staging","Extramural Venous Invasion","NOT_YET_RECRUITING","2026-01-06",{"date":130,"type":131},"2026-01-15","ACTUAL",{"date":133,"type":118},"2026-02",{"date":135,"type":118},"2026-05",{"name":5,"class":6},4]