Rhomboid Intercostal Block With Sub-Serratus Plane Block Versus Erector Spinae Block

ConditionBreast Cancer Patients

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexFemale

Age18-65

SponsorCairo University

About this trial

This study compares two nerve block techniques-Rhomboid Intercostal with Sub-Serratus Plane Block versus Erector Spinae Plane Block-for pain relief after breast cancer surgery. It aims to determine which method provides better postoperative pain control, reduces opioid use, and improves recovery in patients undergoing modified radical mastectomy at the National Cancer Institute, Cairo University.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Female breast cancer patients undergoing Modified Radical Mastectomy (MRM)

Disqualifiers

Patient refusal

Trial design

Design model

Parallel

Treatments tested in this trial

Rhomboid Intercostal Block with Sub-Serratus Plane Block
Procedure/Surgery
Ultrasound-guided regional anesthesia combining two injections: Rhomboid Intercostal Block (20 mL of 0.25% bupivacaine injected between rhomboid major and intercostal space) Sub-Serratus Plane Block (20 mL of 0.25% bupivacaine injected between serratus anterior and ribs). Both performed 30-45 minutes before Modified Radical Mastectomy under general anesthesia.
Erector Spinae Plane Block
Procedure/Surgery
Ultrasound-guided regional block with 30 mL of 0.25% bupivacaine injected into the paraspinal plane at the T4-T5 level, between the erector spinae muscle and the transverse processes. Performed 30-45 minutes prior to general anesthesia for Modified Radical Mastectomy.

Treatment groups

80 Participants

are divided into 2 treatment groups

Group A: Rhomboid Intercostal Block with Sub-Serratus Plane BlockExperimental treatment 1 intervention

Group B: Erector Spinae Plane BlockActive comparator 1 intervention

Trial outcomes

Primary outcomes

Postoperative Pain Scores

Postoperative pain will be assessed using the Visual Analog Scale (VAS) both at rest (static) and during movement (dynamic). Assessments will be conducted at 2, 6, 12, and 24 hours following surgery. The VAS is a 10-centimeter scale, where 0 indicates "no pain" and 10 indicates the "worst imaginable pain." Unit of Measure: VAS score (0-10)

Time frame

First 24 hours postoperatively

Total Opioid Consumption

The total amount of opioid analgesics administered within the first 24 postoperative hours will be recorded for each patient. All opioid dosages will be converted to intravenous morphine equivalents for standardization. Unit of Measure: Milligrams of intravenous morphine equivalents (mg)

Time frame

First 24 hours postoperatively

Sponsors and contacts

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Cairo University

Lead sponsor

Source ClinicalTrials.gov

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