About this trial
This project proposes to establish a prospective cohort of MIA based on a preexisting multicenter MIA database and to combine multidimensional methods such as high-resolution magnetic resonance, hemodynamics, ambulatory blood pressure, and imaging histology to study aneurysm instability.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age 18-80 years old, male or infertile female;
Diagnosed as IA (intracranial aneurysm) through CTA, MRA, or DSA; And it is suitable for endovascular intervention treatment
The patient and/or their legal representative or guardian fully understand the research purpose, voluntarily participate and sign informed consent Books;
Patients willing to cooperate with high-resolution magnetic resonance imaging.
Disqualifiers
AVM (arteriovenous malformation), Moyamoya disease, or DAVF (dural arteriovenous fistula) related aneurysms;
Patients with contraindications for high-resolution magnetic resonance imaging;
Participants in clinical trials of other drugs or medical devices;
Patients with severe underlying diseases and extremely poor clinical conditions who cannot tolerate general anesthesia surgery;
Trial population
Inclusion Criteria: 1\. be older than 18 years of age; 2. complete a high-resolution magnetic resonance exam Exclusion Criteria: 1\. aneurysm combined with other cerebrovascular diseases; 2. substandard image quality
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
High resolution MRI aneurysm features
Enhancement grade was defined as follows: grade 0 for none enhancement, grade 1 for focal enhancement, involved the neck, the intermediate portion, the dome, or a bleb;grade 2 for thin annular enhancement (maximum thickness≤1 mm) , grade 3 for thick annular enhancement(maximum thickness\>1 mm) .
Secondary outcomes
postoperative mRS score
MRS score definition: The MRS score, also known as the Modified Rankin Scale, is a scale used to evaluate the neurological recovery status of stroke patients. It is divided into seven levels, Level 0: completely asymptomatic. Level 1: Despite symptoms, without obvious disabilities, able to complete all frequently engaged work and activities. Level 2: Mild disability, unable to complete all work and activities, but able to handle personal affairs without the need for assistance from others. Level 3: Moderate disability, requiring assistance from others to walking without assistance. Level 4: Severe disability, unable to walk without the help of others, unable to take care of one's own needs. Level 5: Severe disability, bedridden, urinary and fecal incontinence, requiring continuous care, and requiring multiple 24-hour care from others. Level 6: Death. The higher the mRS score, the worse the patient's prognosis.
postoperative aneurysm occlusion rate
Raymond classification, grade I: complete embolism; Grade II: residual aneurysm neck;
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