[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584978":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":21,"locations":10,"responsibleParty":31,"collaborators":10,"id":35,"slug":10,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":41,"sex":42,"minAge":43,"maxAge":44,"enrollmentInfo":45,"targetDuration":10,"studyType":48,"phases":10,"briefSummary":49,"conditions":50,"keywords":10,"overallStatus":52,"whyStopped":10,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"cases with juvenile autoimmune hepatitis",null,"patients who are diagnosed physically, clinically, and histologically with juvenile autoimmune hepatitis",{"label":13,"type":10,"description":14,"interventionNames":10},"control group","children with near-normal liver biopsy",[16,19],{"name":17,"affiliation":5,"role":18},"Howadya Ismail Hassan El Sayed, PhD","STUDY_DIRECTOR",{"name":20,"affiliation":5,"role":18},"Moemen Mostafa Ahmed Hafez, PhD",[22,27],{"name":23,"role":24,"phone":25,"phoneExt":10,"email":26},"Mariam Mohamed Rashwan, bachelor's degree","CONTACT","+20 1158056572","Mariam.rashwan@aun.edu.eg",{"name":28,"role":24,"phone":29,"phoneExt":10,"email":30},"Shimaa Hassan Shaban, PhD","+20 1090651710","shimaahassan@aun.edu.eg",{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mariam Mohamed Rashwan Mohamed","Assistant lecturer","100584978",false,"NCT06896383","Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis","Role of USP35 in the Detection of Ferroptosis in Juvenile Autoimmune Hepatitis: an Immunohistochemical Study","Inclusion Criteria:\n\n* Patients aged between one day and 18 years (children)\n* patients diagnosed clinically and physically with juvenile autoimmune hepatitis including seronegative autoimmune hepatitis cases\n\nExclusion Criteria:\n\n1. Cases with inadequate tissue in the paraffin block\n2. Children with viral hepatitis\n3. patients above the age of 18 years old",true,"ALL","1 Day","18 Years",{"count":46,"type":47},60,"ESTIMATED","OBSERVATIONAL","1. To evaluate the immunohistochemical expression of USP35 in cases of juvenile autoimmune hepatitis and control cases.\n2. To correlate this with the level of necro-inflammation and extent of fibrosis using Massion's trichrome stain in cases of juvenile autoimmune hepatitis.",[51],"Autoimmune Hepatitis","NOT_YET_RECRUITING","2025-03-24",{"date":55,"type":56},"2025-03-26","ACTUAL",{"date":58,"type":47},"2025-11",{"date":60,"type":47},"2027-01",{"name":5,"class":6}]