[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608742":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":18,"responsibleParty":34,"collaborators":7,"id":36,"slug":7,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":7,"eligibilityCriteria":40,"healthyVolunteers":41,"sex":42,"minAge":43,"maxAge":7,"enrollmentInfo":44,"targetDuration":7,"studyType":47,"phases":7,"briefSummary":48,"conditions":49,"keywords":55,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":61,"completionDateStruct":63,"leadSponsor":65,"locationsCount":66},{"fullName":5,"class":6},"RenJi Hospital","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"nothing","This is an observational study.",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"融 黄, Ph.D","CONTACT","+862168383816","11084@renji.com",[19],{"facility":20,"status":21,"city":22,"state":7,"zip":7,"country":23,"countryCode":24,"cosmosGeoPoint":25,"geoPoint":30,"contacts":31},"Department of Geriatrics, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.","RECRUITING","Shanghai","China","CN",{"type":26,"coordinates":27},"Point",[28,29],121.45806,31.22222,{"lat":29,"lon":28},[32],{"name":33,"role":15,"phone":16,"phoneExt":7,"email":17},"Rong Huang, Ph.D",{"type":35,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100608742",false,"NCT07205510","Sarcopenia, Metabolic Diseases, and Integrated Aging Longitudinal Evaluation (SMILE)","Inclusion Criteria:\n\nAdults aged 18 and over\n\nExclusion Criteria:\n\n1. Does not cooperate in signing the informed consent form;\n2. Does not possess legal capacity;\n3. In a state of loss of consciousness;\n4. Suffering from severe mental illness, unable to communicate normally;\n5. The researcher believes that the subject has a disease that affects the assessment of results and is unsuitable for inclusion.",true,"ALL","18 Years",{"count":45,"type":46},10000,"ESTIMATED","OBSERVATIONAL","This study aims to establish an ambispective cohort platform centered on the pathological axis of \"sarcopenia-metabolic disorders-aging progression\", integrating multimodal data including demographic characteristics, lifestyle factors, clinical phenotypes, laboratory tests, medical imaging, and biospecimens. Namely 'Sarcopenia, Metabolic Diseases, and Integrated Aging Longitudinal Evaluation (SMILE)'.",[50,51,52,53,54],"Sarcopenia","Metabolic Diseases","All-cause Mortality","Aging","Cardiometabolic Diseases",[50,51,53,56,54],"All-cause mortality","2025-09-25",{"date":59,"type":60},"2025-10-03","ACTUAL",{"date":62,"type":60},"2020-12-01",{"date":64,"type":46},"2040-12-31",{"name":5,"class":6},1]