[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100495134":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":17,"locations":26,"responsibleParty":43,"collaborators":46,"id":49,"slug":7,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":63,"studyType":64,"phases":7,"briefSummary":65,"conditions":66,"keywords":70,"overallStatus":29,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"University of Aarhus","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"cytology, p16\u002Fki67 dual stain cytology (DS), extended genotyping, DNA methylation, viral load,","p16\u002FKi67 dual stain cytology, extended genotyping and DNA methylation will be performed from the residual cell-pellet from the HPV-positive screening samples. If no cytology-triage testing is performed as a part of the screening algorithm, a cytology will be performed at inclusion. If any residual material is left after DS, extended genotyping and DNA methylation, it will be stores at -80 degrees for future purposes.",[13],{"name":14,"affiliation":15,"role":16},"mette tranberg, post doc","Randers Regional Hospital, Denmark","PRINCIPAL_INVESTIGATOR",[18,22],{"name":14,"role":19,"phone":20,"phoneExt":7,"email":21},"CONTACT","40113676","mettrani@rm.dk",{"name":23,"role":19,"phone":24,"phoneExt":7,"email":25},"Line Winther Gustafson, MD","+4578420264","Line.Winther@skejby.rm.dk",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Department of Pathology","RECRUITING","Randers","Central Jutland","8930","Denmark","DK",{"type":36,"coordinates":37},"Point",[38,39],10.03639,56.4607,{"lat":39,"lon":38},[42],{"name":14,"role":19,"phone":20,"phoneExt":7,"email":21},{"type":16,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Mette Tranberg Nielsen","post doc, PhD",[47],{"name":48,"class":6},"Randers Regional Hospital","100495134",false,"NCT05727228","Screening Triage and Risk Stratification","Improving Screening Triage in Older Postmenopausal HPV-screen-positive Women Aged 50-64 and Risk-stratification of Women Aged 23-64 After Excision","I-share","Inclusion Criteria:\n\n* HPV-screen-positive (aged 50-64)\n* Women who undergo test-of-cure (i.e. HPV and cytology) six months after LEEP in Central Denmark Region (aged 23-64)\n* Women who undergo follow-up test (i.e. HPV and cytology) 12 months after LEEP\n* A valid cytology-triage result (aged 23-64)\n\nExclusion Criteria:\n\n* Listed in the registry as a person who have rejected to participate in research\n* Invalid cytology and HPV result six months after LEEP\n* No residual material available",true,"FEMALE","23 Years","64 Years",{"count":61,"type":62},5000,"ESTIMATED","5 Years","OBSERVATIONAL","* To investigate the performance of cytology, extended genotyping, p16\u002FKi67 dual stain cytology, DNA methylation and viral load as triage markers in post-menopausal HPV-screen-positive women aged 50-64 years in the organized screening program to predict the risk of developing CIN2+. (work package 1)\n* To investigate the performance of cytology, extended genotyping, p16\u002FKi67 dual stain cytology, DNA methylation and viral load six months after cervical excision to predict the long-term risk of residual\u002Frecurrent CIN2+ lesions among women aged 23-64 (work-package 2)",[67,68,69],"Cervix Cancer","HPV Testing","Postmenopausal Women",[71,72],"mass screening","triage biomarkers","2023-02-03",{"date":75,"type":76},"2023-02-14","ACTUAL",{"date":78,"type":62},"2023-02-27",{"date":80,"type":62},"2027-02",{"name":5,"class":6},1]