[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100436153":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":20,"locations":25,"responsibleParty":46,"collaborators":20,"id":49,"slug":20,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":20,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":57,"maxAge":20,"enrollmentInfo":58,"targetDuration":20,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":68,"overallStatus":28,"whyStopped":20,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Respiratory Function Testing","EXPERIMENTAL","All subjects will receive standard respiratory function testing and ultrasound-based elastography measurements across various behaviors and conditions",[13],"Diagnostic Test: Shear-wave elastography",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","Shear-wave elastography","Ultrasound based imaging of diaphragm muscle activity",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Carlos Matilla, MD, PhD","PRINCIPAL_INVESTIGATOR",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"Mayo Clinic in Rochester","RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-92.4699,44.02163,{"lat":38,"lon":37},[41],{"name":42,"role":43,"phone":44,"phoneExt":20,"email":45},"Carlos B Mantilla","CONTACT","507-255-1612","mantilla.carlos@mayo.edu",{"type":24,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"Carlos B Mantilla, MD, PhD","Principal Investigator","100436153",false,"NCT04959526","Shear-wave Elastography Compared to Respiratory Function Testing","Comparison of Shear-wave Elastography to State-of-the-art Respiratory Function Testing to Measure the Range of Forces Generated by the Diaphragm Muscle","Inclusion Criteria:\n\n\\- Adult male and female healthy volunteers.\n\nExclusion Criteria:\n\n* Volunteers who are pregnant.\n* Volunteers with known pulmonary pathology (COPD, asthma requiring routine treatment).",true,"ALL","18 Years",{"count":59,"type":60},24,"ESTIMATED","INTERVENTIONAL",[63],"NA","The purpose of this study is to evaluate the relationship between transdiaphragmatic pressure (Pdi) and diaphragm shear-wave elastography (SWE) during state-of-the-art respiratory muscle testing including volitional efforts (e.g., maximal inspiratory pressure, maximal expiratory pressure, Valsalva maneuver), as well as maximal phrenic nerve stimulation.",[66,67],"Respiratory Function Loss","Respiratory Complication",[69,70],"Elastography","Ultrasound","2026-03-12",{"date":73,"type":74},"2026-03-16","ACTUAL",{"date":76,"type":74},"2021-07-28",{"date":78,"type":60},"2026-12",{"name":5,"class":6},1]