[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100373409":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":29,"responsibleParty":47,"collaborators":49,"id":53,"slug":10,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":10,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":10,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Johns Hopkins University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"HIV",null,"Participants (ages 60 and above) with HIV",{"label":13,"type":10,"description":14,"interventionNames":10},"Control","Participants (ages 60 and above) without HIV",[16],{"name":17,"affiliation":5,"role":18},"Robert G Weiss, MD","PRINCIPAL_INVESTIGATOR",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Maria Esteban, RN, BSN","CONTACT","410-955-1160","mesteba1@jh.edu",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":28},"Tricia Steinberg, RN, MSN","443-287-3469","asteinb3@jhmi.edu",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Johns Hopkins Hospital","RECRUITING","Baltimore","Maryland","21287","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-76.61219,39.29038,{"lat":42,"lon":41},[45],{"name":46,"role":22,"phone":27,"phoneExt":10,"email":28},"Tricia Steinberg, MSN",{"type":48,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[50],{"name":51,"class":52},"National Institute on Aging (NIA)","NIH","100373409",false,"NCT04142047","Skeletal Muscle Energetics and Fatiguability in Older Individuals","Inclusion Criteria:\n\n* Participants who are \\>= 60 years of age\n* HIV serostatus positive participants on stable antiretroviral therapy (ART) (no regimen change in last month) with undetectable HIV viral load (\\\u003C100 copies).\n* HIV serostatus negative participants\n\nExclusion Criteria:\n\n* Unable to understand the risks, benefits, and alternatives of participation and give meaningful consent\n* Contraindications to MRI\n* Significant cardiovascular, pulmonary or musculoskeletal or orthopedic disease that significantly limits exercise capacity\n* Significant lower extremity peripheral vascular disease.\n* Weight greater than 350 lbs\n* Cognitive or speech impairments that would limit completion of questionnaires or fatigue reporting.",true,"ALL","60 Years","90 Years",{"count":63,"type":64},200,"ESTIMATED","OBSERVATIONAL","The investigators are studying whether metabolic abnormalities in calf (leg) muscle in older people with and others without HIV are associated with decreased abilities to exercise.",[9,68],"HIV Infections","2026-06-04",{"date":71,"type":72},"2026-06-08","ACTUAL",{"date":74,"type":72},"2019-09-05",{"date":76,"type":64},"2027-07-01",{"name":5,"class":6},1]