[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608201":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":16,"slug":10,"hasResults":17,"nctId":18,"briefTitle":19,"officialTitle":19,"acronym":10,"eligibilityCriteria":20,"healthyVolunteers":17,"sex":21,"minAge":22,"maxAge":10,"enrollmentInfo":23,"targetDuration":10,"studyType":26,"phases":10,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Adult patients with major depressive disorder",null,"The study sample will include 90 psychiatric patients recruited from the outpatient and inpatient clinics of Assiut University Hospital, representing males and females aged 18-60 years. All participants will have a confirmed diagnosis of major depressive disorder based on clinical criteria and will be evaluated using standardized psychiatric assessment tools.",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Alzahraa Aref Fouad","resident at the Neuropsychiatry department","100608201",false,"NCT07198477","Sleep Disturbances and Their Association With Serum Magnesium Level in Patients With Major Depressive Disorder","Inclusion Criteria:\n\n* Confirmed diagnosis of major depressive disorder\n\nage 18 years and older\n\nAbility to complete questionnaires (BDI-II and PSQI; validated Arabic versions)\n\nWilling to participate and provide informed consent\n\nExclusion Criteria:\n\n* hronic renal failure or metabolic disorders affecting magnesium balance\n\nCurrent use of medications known to significantly interfere with serum magnesium (e.g., long-term diuretics, proton pump inhibitors) unless stable and documented\n\nPresence of other comorbid psychiatric disorders\n\nCognitive impairment or language difficulties preventing questionnaire completion","ALL","18 Years",{"count":24,"type":25},90,"ESTIMATED","OBSERVATIONAL","This cross-sectional study investigates the relationship between serum magnesium levels and the presence of sleep disturbances among patients with major depressive disorder (MDD).",[29,30],"Depressive Disorder","Sleep Disturbances",[32],"sleep disturbances","NOT_YET_RECRUITING","2025-09-29",{"date":36,"type":37},"2025-09-30","ACTUAL",{"date":39,"type":25},"2026-08-30",{"date":41,"type":25},"2027-12-30",{"name":5,"class":6}]