[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590539":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":7,"responsibleParty":18,"collaborators":7,"id":22,"slug":7,"hasResults":23,"nctId":24,"briefTitle":25,"officialTitle":26,"acronym":27,"eligibilityCriteria":28,"healthyVolunteers":23,"sex":29,"minAge":30,"maxAge":31,"enrollmentInfo":32,"targetDuration":7,"studyType":35,"phases":7,"briefSummary":36,"conditions":37,"keywords":42,"overallStatus":51,"whyStopped":7,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":7},{"fullName":5,"class":6},"Uppsala University","OTHER",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Christian Benedict, PhD","CONTACT","+46 18 471 43 30","christian.benedict@farmbio.uu.se",{"name":15,"role":11,"phone":16,"phoneExt":7,"email":17},"Bettina Sielaff, MD","+46 076-1411449","bettina.sielaff@regiondalarna.se",{"type":19,"investigatorFullName":20,"investigatorTitle":21,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Christian Benedict","Associate Professor","100590539",false,"NCT06968728","Sleep, Glucose, and Brain Health in Obesity and Overweight Individuals","The Interplay Between Sleep Disturbances, Glucose Regulation, and Brain Health in Individuals With Overweight and Obesity","NNF","* Be between 40 and 65 years of age\n* Be classified as having normal weight, overweight, or obesity\n* Not be pregnant\n* Not be currently using glucose-lowering medications or undergoing glucose therapy\n* Not have a diagnosis of type 1 or type 2 diabetes mellitus\n* Not have kidney disease, thyroid disorders, or inflammatory bowel disease\n* Not have undergone bariatric surgery\n* Not actively participating in a weight-loss diet\n* Not using medications that affect glucose levels or taking sleep-inducing pills\n* Not working night shifts\n* Not have traveled across time zones in the past 3 months\n* Not have any severe chronic medical illnesses or severe psychiatric disorders\n* Be able and willing to wear all required study monitoring devices\n* Own a smartphone with Bluetooth capability","ALL","40 Years","65 Years",{"count":33,"type":34},400,"ESTIMATED","OBSERVATIONAL","The primary aim of the NNF study is to investigate both cross-sectional and longitudinal associations between sleep patterns-measured over two consecutive weeks at baseline and again one year later-and indicators of glycemic control and brain health in a cohort of middle-aged adults. Through this effort, the investigators hope to identify potential sleep-related biomarkers and behavioral targets for early intervention to support metabolic and cognitive health.",[38,39,40,41],"Obesity and Overweight","Type 2 Diabetes","Sleep","Brain Health",[43,44,45,46,47,48,49,50],"obesity","overweight","type 2 diabetes","glucose control","brain health","diet","sleep disruption","gut microbiota","NOT_YET_RECRUITING","2025-05-13",{"date":54,"type":55},"2025-05-18","ACTUAL",{"date":57,"type":34},"2025-05-15",{"date":59,"type":34},"2030-01-15",{"name":5,"class":6}]