This study aims to evaluate the feasibility of Laser Speckle Contrast Imaging for perioperative perfusion assessment of the lower extremity before, during, and after revascularization.
Scheduled for lower-extremity revascularization
Undergoing pre- and postoperative indocyanine near-infrared fluorescence perfusion measurements
None
The population of this study will undergo a revascularization of the lower extremity due to peripheral artery disease. Such revascularization can be thrombo-endarterectomy (TEA), or endovascular percutaneous transluminal angioplasty (PTA).
Cohort
Prospective
Laser Speckle Contrast Imaging
Diagnostic testMeasurement with LSCI device
To assess the feasibility and the quantification of laser speckle contrast imaging for monitoring of perfusion of the lower extremities during and following revascularization
Feasibility
Correlation of pre-, intra- and postsurgery laser speckle contrast imaging (LSCI) findings with the pre-, intra- and post-temperature of the patient's foot
Temperature
Comparative analysis of LSCI with standard of care near-infrared fluorescence imaging using ICG
ICG
Exploration of quantitative approaches to LSCI analysis, including assessment of blood flow pulsatility
Correlation of quantified LSCI recordings to clinical outcomes.
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