Split-Belt Gait Retraining in Subacute Stroke

ConditionStroke
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of British Columbia

About this trial

Stroke is a leading cause of long-term disability in adults. Although many individuals regain independent walking ability following stroke, nearly 50% experience persistent gait impairments characterized by asymmetrical walking patterns, slower walking speed, impaired balance, and increased fall risk. These persistent mobility limitations highlight the continued need for innovative rehabilitation strategies that improve gait function during stroke recovery. Split-belt treadmill walking (SBTW), in which each leg walks at a different belt speed, has demonstrated potential to improve step length symmetry in individuals with chronic stroke. However, the effects of SBTW during the subacute stage of stroke recovery, within the first 9 months post-stroke when neuroplasticity may be heightened, remain largely unknown. In addition, previous SBTW studies have not integrated active physiotherapist-led gait retraining into the intervention, despite physiotherapist-led gait rehabilitation representing standard clinical care following stroke. The purpose of this randomized controlled trial is to compare physiotherapist-led gait retraining using a traditional treadmill training protocol to physiotherapist-led gait retraining integrated with a split-belt treadmill training protocol during the first 9 months post-stroke. The study aims to examine the effectiveness of the use of split-belt treadmill training to augment physiotherapist-led gait retraining to improve between-leg gait symmetry and overground walking speed.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

unilateral stroke resulting in hemiparesis

less than 9 months post-stroke

ability to walk ten metres with or without walking aids

ability to stand without support for five minutes

Disqualifiers

medically unfit to participate e.g. cardiac or respiratory disease limiting ability to perform walking tasks

neuromuscular impairment, other than stroke, limiting mobility, e.g. ankle sprain, joint disease such as severe arthritis

cognitive/communication impairment impacting ability to follow instructions

diagnosis of clinical depression or anxiety disorders requiring medication

Trial design

Design model

Parallel

Treatments tested in this trial

  • Split-belt walking training

    Behavioral

    Participants randomized to the split-belt training group will complete 12 sessions of split-belt treadmill walking training over 4 weeks, delivered 3 times per week. Training will be performed on an instrumented split-belt treadmill and will include split-belt and tied-belt walking conditions. A physiotherapist will provide gait retraining during each session.

Treatment groups

30 Participants
are divided into 2 treatment groups
Group A: Split-belt treadmill trainingExperimental treatment 1 intervention
Group B: Traditional treadmill trainingNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Step length symmetry

Time frame
Baseline, immediately post-intervention, and at 1-month follow-up
2

Self-selected gait speeds

Self-selected gait speeds at both comfortable and fast speed will be measured by overground 10 meter walk tests

Time frame
Baseline, immediately post-intervention, and at 1-month follow-up

Secondary outcomes

Other outcomes

Sponsors and contacts

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