Streamlined Treatment and Evidence-based Adolescent Counseling and Medication Support (STREAMS)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age15-19
SponsorCity University of New York, School of Public Health

About this trial

Combination interventions to address mental health and adherence to HIV care in low- and middle-income countries (LMICs), are crucial to achieving the UNAIDS 95-95-95 targets as one in four adolescents living with HIV (ALWHIV) experience poor mental health and this contributes to suboptimal medication adherence and lack of viral suppression. Yet few evidence-based mental health and adherence interventions have been evaluated in sub-Saharan Africa (SSA), the region where the majority of the 1.7 million ALWHIV reside. STREAMS will determine if our streamlined combination intervention approach to mental health screening, provision of evidence-based interpersonal psychotherapy groups (IPT-G), and evidence-based family strengthening, and medication counseling is feasible and efficacious for ALWHIV in Uganda.

Eligibility criteria

Qualifiers

Living with HIV with confirmation by medical report and aware of their status

Living within a family (defined broadly, not necessarily with biological parents); - - Between the ages of 15 to 19 years

Prescribed ART

Score a 10 or greater on the PHQ-9

Disqualifiers

an inability to understand study procedures and participant rights as assessed during informed consent/assent process with the adolescent or caregiver.

Trial design

Treatments tested in this trial

  • Streamlined Suubi+Adherence
  • Streamlined Interpersonal Psychotherapy Groups (IPT-G)

Treatment groups

588 Participants
are divided into 3 treatment groups

Locations

This trial has no locations

Sponsors and collaborators

City University of New York, School of Public Health

Lead sponsor

National Institute of Mental Health (NIMH)

Collaborator

New York University

Collaborator

Washington University Bursky School of Public Health

Collaborator