About this trial
Combination interventions to address mental health and adherence to HIV care in low- and middle-income countries (LMICs), are crucial to achieving the UNAIDS 95-95-95 targets as one in four adolescents living with HIV (ALWHIV) experience poor mental health and this contributes to suboptimal medication adherence and lack of viral suppression. Yet few evidence-based mental health and adherence interventions have been evaluated in sub-Saharan Africa (SSA), the region where the majority of the 1.7 million ALWHIV reside. STREAMS will determine if our streamlined combination intervention approach to mental health screening, provision of evidence-based interpersonal psychotherapy groups (IPT-G), and evidence-based family strengthening, and medication counseling is feasible and efficacious for ALWHIV in Uganda.
Eligibility criteria
Qualifiers
Living with HIV with confirmation by medical report and aware of their status
Living within a family (defined broadly, not necessarily with biological parents); - - Between the ages of 15 to 19 years
Prescribed ART
Score a 10 or greater on the PHQ-9
Disqualifiers
an inability to understand study procedures and participant rights as assessed during informed consent/assent process with the adolescent or caregiver.
Trial design
Treatments tested in this trial
- Streamlined Suubi+Adherence
- Streamlined Interpersonal Psychotherapy Groups (IPT-G)
Treatment groups
Locations
Sponsors and collaborators
City University of New York, School of Public Health
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
New York University
Collaborator
Washington University Bursky School of Public Health
Collaborator