Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorGuy's and St Thomas' NHS Foundation Trust
About this trial
There are over 700,000 UK hospital admissions every year with lung disease symptoms. Two of the most common lung diseases contributing to these numbers are asthma and chronic obstructive pulmonary disease (COPD). The immunopathology of these diseases is not fully understood. Matched samples from the respiratory tract and circulation will be used to identify immune patterns throughout the respiratory system to elucidate the immunopathology of airway disease.
Eligibility criteria
Qualifiers
Participant is willing and able to give informed consent for participation in the study
Aged 18 years or above
Patient: known or suspected airway disease
Healthy volunteer: considered to be in good health with no significant comorbidity (immune disorder, cancer etc.)
Disqualifiers
Known or suspected current pulmonary tuberculosis, HIV (human immunodeficiency virus), Hepatitis B Virus, Hepatitis C Virus.
Surgery within the preceding 6 weeks
Participants who are pregnant
History of psychiatric, medical, or surgical disorders that in the opinion of the chief investigator may interfere with sample collection, undergo a bronchoscopy, or may compromise study completion or data collection
Trial design
Treatments tested in this trial
- Not listed
Trial groups
230 Participants
are grouped into 2 trial groupsSponsors and collaborators
Guy's and St Thomas' NHS Foundation Trust
Lead sponsor
King's College London
Collaborator
Source ClinicalTrials.gov