[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601721":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":20,"collaborators":11,"id":22,"slug":11,"hasResults":23,"nctId":24,"briefTitle":25,"officialTitle":25,"acronym":11,"eligibilityCriteria":26,"healthyVolunteers":27,"sex":28,"minAge":29,"maxAge":30,"enrollmentInfo":31,"targetDuration":11,"studyType":34,"phases":35,"briefSummary":37,"conditions":38,"keywords":11,"overallStatus":42,"whyStopped":11,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":11},{"fullName":5,"class":6},"Xijing Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Safety assessment","EXPERIMENTAL",null,[13],"Diagnostic Test: 68Ga-ACC-DE\u002F68Ga-FASN-DE\u002F68Ga-ACLY-DE PET\u002FCT",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DIAGNOSTIC_TEST","68Ga-ACC-DE\u002F68Ga-FASN-DE\u002F68Ga-ACLY-DE PET\u002FCT","Recruit 15 healthy adult volunteers, divided into three groups, to undergo dynamic PET\u002FCT (1 hour) and static PET\u002FCT (2 hours and 3 hours) imaging with 68Ga-ACC-DE, 68Ga-FASN-DE, or 68Ga-ACLY-DE, respectively, to assess safety, biodistribution, and radiation dosimetry, laying the foundation for subsequent studies.",[9],{"type":21,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100601721",false,"NCT07114172","Study of Melanoma-Resistant PET Monitoring Based on Key Rate-limiting Enzymes for Fatty Acid Metabolism in Healthy Volunteers","Inclusion Criteria:\n\n* Age: 18 to 65 years old (including the boundary values); Gender: Male or female; Weight: Male weight ≥ 50 kg, female weight ≥ 45 kg, and body mass index (BMI = weight (kg) \u002F height² (m²)) within the range of 18.0 to 28.0 kg\u002Fm² (including boundary values); Participants must fully understand and voluntarily participate in this experiment and sign an informed consent form.\n\nExclusion Criteria:\n\n* Individuals who cannot tolerate intravenous administration (e.g., those with a history of fainting from needles or blood); Individuals with alcohol allergies; Pregnant or breastfeeding women; Individuals with severe diseases of the heart, kidneys, lungs, blood vessels, nervous system, or mental health, immune deficiency diseases, or hepatitis\u002Fcirrhosis; Individuals whom the investigator deems unsuitable for or unable to complete PET or other imaging examinations for special reasons; Other circumstances deemed by the investigator to be unsuitable for participation in this study.",true,"ALL","18 Years","65 Years",{"count":32,"type":33},15,"ESTIMATED","INTERVENTIONAL",[36],"NA","This is a small-sample safety study involving 15 healthy volunteers who were divided into groups and underwent 68Ga-ACC-DE, 68Ga-FASN-DE, and 68Ga-ACLY-DE PET\u002FCT imaging for safety, biodistribution, and radiation dosimetry assessments, laying the foundation for subsequent studies on the efficacy of resistance monitoring in melanoma targeted therapy.",[39,40,41],"Melanoma (Skin Cancer)","Health Volunteers","PET \u002F CT","NOT_YET_RECRUITING","2025-08-08",{"date":45,"type":46},"2025-08-11","ACTUAL",{"date":48,"type":33},"2025-08-15",{"date":50,"type":33},"2025-10-15",{"name":5,"class":6}]