Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Bordeaux

About this trial

Glioblastomas are the most frequent and aggressive malignant tumors of the CNS in adults, with almost systematic relapse despite treatment with surgery followed by radio-chemotherapy (STUPP protocol). The aim of this study is to better characterize transcriptomic, proteomic and metabolic changes in relapsed glioblastoma compared to the initial tumor, in order to identify new prognostic markers and potential new therapeutic targets.

Eligibility criteria

Qualifiers

age > 18 years

surgery for both primary and recurrent glioblastoma between 2005 and 2023 at the CHU de Bordeaux

Disqualifiers

systemic therapy received for non-glioblastoma tumor

Trial design

Treatments tested in this trial

  • Relapsed glioblastoma

Treatment groups

40 Participants
are divided into 1 treatment group

Sponsors and collaborators