Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorKliniken Beelitz GmbH

About this trial

This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.

Eligibility criteria

Qualifiers

diagnosis of probable or possible multiple system atrophy according to current consensus criteria (Gilman et al. 2008) or

diagnosis of probable or possible PSP according to the the Movement Disorders Society (MDS) diagnostic criteria (Höglinger et al. 2017) or

diagnosis of Parkinson's disease according to the MDS diagnostic criteria (Postuma et al 2015)

Hoehn and Yahr Stage within the range of I-V or

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

350 Participants
are grouped into 5 trial groups

Sponsors and collaborators

Kliniken Beelitz GmbH

Lead sponsor

University Hospital Muenster

Collaborator

Medical University of Warsaw

Collaborator

Hannover Medical School

Collaborator

University of Ulm

Collaborator

Medical University Innsbruck

Collaborator

University Hospital Carl Gustav Carus

Collaborator

University of Barcelona

Collaborator

Seoul National University Hospital

Collaborator

Gifu University Graduate School of Medicine

Collaborator

University of Bologna

Collaborator

Tel Aviv University

Collaborator

Asklepios Kliniken Hamburg GmbH

Collaborator

Asklepios Fachklinikum Stadtroda

Collaborator

Klinikum Osnabrück

Collaborator