[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100395729":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":34,"centralContacts":38,"locations":47,"responsibleParty":67,"collaborators":70,"id":78,"slug":33,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":79,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":33,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":98,"overallStatus":50,"whyStopped":33,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"University of New Mexico","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental: Active cathodal tDCS + Speech-language training","ACTIVE_COMPARATOR","In this arm, 31 patients with stroke induced Aphasia will undergo 15 sessions of active tDCS (x 30 minutes of stimulation) combined with 1 hour simultaneous speech-language training on consecutive weekdays.",[13],"Device: Active Comparator: Experimental: Active cathodal tDCS + language training",{"label":15,"type":16,"description":17,"interventionNames":18},"Comparator: Placebo cathodal tDCS + Speech-language training","SHAM_COMPARATOR","In this arm, 31 patients with stroke induced Aphasia will undergo 15 sessions of sham tDCS (x 30 minutes sham) combined with 1 hour simultaneous speech-language training on consecutive weekdays..",[19],"Behavioral: Sham Comparator: Placebo cathodal tDCS + Speech and language",[21,28],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Active Comparator: Experimental: Active cathodal tDCS + language training","Cathodal tDCS raises neuronal membrane potentials, leading to decreased probability of depolarization from incoming stimuli.\n\nSpeech and Language training involves a combined semantic feature analysis and phonological components analysis treatment.",[9],[27],"Behavioral: Speech and Language Training",{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"BEHAVIORAL","Sham Comparator: Placebo cathodal tDCS + Speech and language","Speech and Language training involves a combined semantic feature analysis and phonological components analysis treatment. .",[15],null,[35],{"name":36,"affiliation":5,"role":37},"Jessica Richardson, Ph.D.","PRINCIPAL_INVESTIGATOR",[39,43],{"name":36,"role":40,"phone":41,"phoneExt":33,"email":42},"CONTACT","505 277-1765","jdrichardson@unm.edu",{"name":44,"role":40,"phone":45,"phoneExt":33,"email":46},"Honey Hubbard","505-433-7766","hhubbard@unm.edu",[48],{"facility":49,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"University of New Mexico Center for Brain Recovery and Repair","RECRUITING","Albuquerque","New Mexico","87106","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-106.65114,35.08449,{"lat":60,"lon":59},[63],{"name":64,"role":40,"phone":65,"phoneExt":33,"email":66},"Darbi Gill","505-925-4043","DMGill@salud.unm.edu",{"type":37,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"Jessica Richardson","Assistant Professor: SOM Neurosurgery",[71,74,76],{"name":72,"class":73},"National Institutes of Health (NIH)","NIH",{"name":75,"class":73},"National Institute of General Medical Sciences (NIGMS)",{"name":77,"class":73},"National Institute on Deafness and Other Communication Disorders (NIDCD)","100395729",false,"NCT04432883","Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.","Targeted Transcranial Direct Current Stimulation to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia","AphasiatDCS","Inclusion Criteria:\n\n1. aged 25-85\n2. must be greater than 6 months post-stroke\n3. must have a diagnosis of aphasia based on impaired performance on the Western Aphasia Battery-Revised, Boston Naming Test, or during discourse production\n4. must be left-hemisphere dominant as demonstrated by aphasia onset subsequent to left hemisphere damage\n5. must be stimulable for naming\n\nExclusion Criteria:\n\n1. comorbid neurological disease.\n2. damage to the anterior right hemisphere.\n3. significant mood disorder.\n4. substance\u002Falcohol dependence or abuse within the past year\n5. presence of any implanted electrical device or contraindications to tDCS or MRI\n6. recent medical instability (within 4 weeks)\n7. pregnancy","ALL","25 Years","85 Years",{"count":89,"type":90},50,"ESTIMATED","INTERVENTIONAL",[93],"NA","62 patients who are one year post stroke and have Aphasia as a result of that stroke will be recruited. Participants will have 4 assessment sessions and 15 treatment sessions. The TDCS will be to right Inferior Frontal Gyrus (IFG) (25 active, 25 sham) for 15 days. A combined semantic feature analysis\u002Fphonological components analysis treatment will be paired with the stimulation. Two assessment sessions will be pretreatment, 1 session immediately post-treatment, and 1 session at 3 months follow-up.",[96,97],"Stroke","Aphasia",[96,97,99,100,101],"brain stimulation","communication problems","speech and language therapy","2026-05-20",{"date":104,"type":105},"2026-05-22","ACTUAL",{"date":107,"type":105},"2022-10-18",{"date":109,"type":90},"2027-04-30",{"name":5,"class":6},1]