[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100605233":3},{"organization":4,"armGroups":7,"interventions":21,"overallOfficials":36,"centralContacts":41,"locations":49,"responsibleParty":64,"collaborators":66,"id":70,"slug":27,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":9,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":27,"enrollmentInfo":78,"targetDuration":27,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":91,"whyStopped":27,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Fondazione Don Carlo Gnocchi Onlus","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"TRUST_ME","EXPERIMENTAL","A cycle of motor and cognitive activities delivered at home through a telerehabilitation approach using the Maia platform by ABmedica (https:\u002F\u002Fabmedica.it\u002Fprodotti-ab-medica\u002Fmaia). The treatment will last 5 weeks with a frequency of three sessions a week (1 synchronous and 2 asynchronous).",[13,14],"Device: RICORDO-DTx system","Device: HOMING system",{"label":16,"type":17,"description":18,"interventionNames":19},"Treatment as Usual","PLACEBO_COMPARATOR","Home-based training instructions \"as usual\", consisting of multimedia content (i.e., videos of the educational\u002Frehabilitation activities) delivered asynchronously via telemedicine platfom. The treatment will last 5 weeks with a frequency of three sessions a week.",[20],"Device: Home-based training program",[22,28,32],{"type":23,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"DEVICE","RICORDO-DTx system","Participants with will undergo a cognitive enhancement program using the Astir RICORDO-DTx system (http:\u002F\u002Fwww.ricordo-dtx.com), which allows for the personalization of rehabilitative content based on the needs of the target population and can be delivered remotely.",[9],null,{"type":23,"name":29,"description":30,"armGroupLabels":31,"otherNames":27},"HOMING system","Participants will also undergo motor rehabilitation sessions focused on improving balance, gait, and muscular endurance using the HOMING system (https:\u002F\u002Fwww.tecnobody.com\u002Fhoming).",[9],{"type":23,"name":33,"description":34,"armGroupLabels":35,"otherNames":27},"Home-based training program","Subjects will view videos on Tablet. The treatment will be provided via a digital medicine platform on a mobile device (tablet).",[16],[37],{"name":38,"affiliation":39,"role":40},"Francesca Baglio","IRCCS Fondazione Don Carlo Gnocchi ONLUS","PRINCIPAL_INVESTIGATOR",[42,46],{"name":38,"role":43,"phone":44,"phoneExt":27,"email":45},"CONTACT","+390240308952","fbaglio@dongnocchi.it",{"name":47,"role":43,"phone":27,"phoneExt":27,"email":48},"Federica Rossetto","frossetto@dongnocchi.it",[50],{"facility":39,"status":27,"city":51,"state":27,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Milan","20148","Italy","IT",{"type":56,"coordinates":57},"Point",[58,59],9.18951,45.46427,{"lat":59,"lon":58},[62,63],{"name":38,"role":43,"phone":44,"phoneExt":27,"email":45},{"name":38,"role":40,"phone":27,"phoneExt":27,"email":27},{"type":65,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR",[67],{"name":68,"class":69},"Astir s.r.l.","INDUSTRY","100605233",false,"NCT07159854","Telerehabilitation in Central and Peripheral Neurological Sequelae From Chemotherapy","TeleRehabilitation: an Innovative User-centered STrategic Approach for the treatMent of Central and Peripheral Neurological sEquelae From Chemotherapy - TRUST_ME","Inclusion Criteria:\n\n* Adult subjects (\\>18 years old) with central and\u002For peripheral neurotoxic sequelae following a history of cancer treated with chemotherapeutic agents (Cisplatin and Taxanes), in accordance with the criteria of the International Cognitive Cancer Task Force (Wefel et al., 2011. 10.1016\u002FS1470-2045(10)70294-1)\n* agreement to participate with the signature of the informed consent form;\n\nExclusion Criteria:\n\n* Ongoing chemotherapy treatment;\n* Pre-existing neurological or psychiatric comorbidities (e.g., epilepsy, post-stroke disability, neurodegenerative diseases, genetically based polyneuropathy);\n* Severe visual or hearing impairments that could interfere with the use of technology;\n* Severe cognitive impairment (Mini-Mental State Examination score \\\u003C18);\n* Severe postural disability associated with a high risk of falling at home, as documented in the clinical evaluation;\n* Contraindications to undergoing MRI examination;\n* Ongoing rehabilitation treatment.","ALL","18 Years",{"count":79,"type":80},60,"ESTIMATED","INTERVENTIONAL",[83],"NA","The goal of this clinical trial is to validate the use of innovative tele-rehabilitation (TR) models in terms of efficiency and effectiveness in a pilot cohort of subjects with central and peripheral chemotherapy-induced neurotoxicity. Participants will be randomized (with an allocation ratio of 1:1) into the experimental group (TRUST\\_ME - 15 sessions of motor and cognitive activities delivered at home through a TR approach using the Maia platform) and Treatment as Usual (15 sessions of multimedia content of educational\u002Frehabilitation activities delivered via telemedicine platfom). It expected that the TR system to be considered acceptable in terms of efficiency (usability and acceptability of the technologies) and clinically effective, with positive impacts on both quality of life and central and peripheral functioning in these patients.",[86],"Chemotherapy-induced Neurotoxicity",[88,89,90],"Chemotherapy-induced neurotoxicity","rehabilitation","telerehabilitation","NOT_YET_RECRUITING","2025-08-29",{"date":94,"type":95},"2025-09-08","ACTUAL",{"date":97,"type":80},"2025-09-01",{"date":99,"type":80},"2026-08-31",{"name":5,"class":6},1]