The Chocolate Almond Study - Relating Chewing to Satiation and Postprandial Response
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorUniversity of Guelph
About this trial
The goal of this clinical trial is to relate chewing behaviours to food intake and postprandial response for a texturally complex food matrix (almonds in white chocolate) in healthy young females. The main questions it aims to answer are:
* Does the presence or preparation of almonds (whole versus chopped) influence satiation, i.e., the amount consumed at an ad libitum meal? * What is the correlation between chewing behaviour, satiation, and changes in postprandial glucose, triacylglycerols, and satiety ratings? Participants will attend the research centre fasted on three occasions to consume an ad libitum meal, complete questionnaires, and provide fasting and postprandial finger prick blood samples.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
BMI between 18.5-27.9 kg/m² or waist circumference less than 88 cm
No known food allergies or sensitivities
Non-restrained eaters based on the Three Factor Eating Questionnaire
No history of gastrointestinal diseases that may interfere with eating behaviour or digestion
Disqualifiers
Diabetes or other metabolic disorders affecting glycemia and overall cardiometabolic health
Any food allergies, intolerance, or sensitivities
Any life-threatening allergy
Pregnant or breastfeeding
Trial design
Design model
Crossover
Treatments tested in this trial
200 g serving of white chocolate-based confection product
Other intervention200 g serving of white chocolate-based confection product
Treatment groups
35 Participants
are divided into 3 treatment groupsGroup A: White chocolate with whole almondsExperimental treatment 1 intervention
Group B: White chocolate without almondsExperimental treatment 1 intervention
Group C: White chocolate with chopped almondsExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Satiation
Weight (g) of chocolate confection consumed during ad libitum meal
Time frame
BaselineSecondary outcomes
1
Borg rating of perceived exertion
Paper scale rating of effort required to chew the meal where 0 = No effort at all and 10 = Very very severe chewing effort
Time frame
Immediately after the ad libitum meal is consumed2
Eating rate
Calculated from time of eating
Time frame
Immediately after the ad libitum meal is consumed3
Blood glucose
Based on finger prick blood analysis
Time frame
Baseline and 2 hours later4
Blood triacylglycerols
Based on finger prick blood analysis
Time frame
Baseline and 3 hours laterSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov