[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100614082":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":16,"slug":10,"hasResults":17,"nctId":18,"briefTitle":19,"officialTitle":20,"acronym":10,"eligibilityCriteria":21,"healthyVolunteers":17,"sex":22,"minAge":10,"maxAge":23,"enrollmentInfo":24,"targetDuration":10,"studyType":27,"phases":10,"briefSummary":28,"conditions":29,"keywords":32,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Preterm neonates",null,"Preterm neonates receiving standard caffeine citrate therapy for apnea of prematurity, including a loading dose of 20-25 mg\u002Fkg followed by maintenance dosing (5-10 mg\u002Fkg daily). Cardiovascular parameters and side effects are monitored longitudinally.",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Margret Azer","Resident at Pediatric Department, Assiut University","100614082",false,"NCT07274969","The Effect of Caffeine Therapy in Cardiovascular Stability in Preterm Neonates at Assiut University Children Hospital NICU","The Effect of Caffeine Therapy in Cardiovascular Stability in Preterm Neonates: a Prospective Study at the Neonatal Intensive Care Unit of Assiut University Children Hospital","Inclusion Criteria:\n\n* Preterm neonates with gestational age \\\u003C37 weeks\n* Receiving caffeine therapy for apnea of prematurity\n* Hemodynamically stable before caffeine initiation\n\nExclusion Criteria:\n\n* Presence of major congenital anomalies\n* Use of vasopressors at baseline\n* Severe intraventricular hemorrhage (Grade III-IV)","ALL","37 Weeks",{"count":25,"type":26},40,"ESTIMATED","OBSERVATIONAL","Preterm neonates younger than 37 weeks gestational age receiving caffeine therapy for apnea of prematurity in a NICU setting.",[30,31],"Preterm Neonates","Apnea of Prematurity",[9,33],"apnea of prematurity","NOT_YET_RECRUITING","2025-12-09",{"date":37,"type":38},"2025-12-10","ACTUAL",{"date":40,"type":26},"2026-06-30",{"date":42,"type":26},"2027-12-30",{"name":5,"class":6}]