The Effect of Graded Forced Expiration on Intraocular Pressure
ConditionIntraocular Pressure
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUşak University
About this trial
The primary objective of this study is to utilize the Airofit device to systematically measure and characterize the changes in intraocular pressure across its six different levels of forced expiration. This investigation will provide crucial quantitative data on the IOP-respiratory effort relationship, enhancing our understanding of IOP dynamics during controlled respiratory stress and establishing a new, standardized paradigm for such research.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged 18 years or older.
Willing and able to provide informed consent.
Have a best-corrected visual acuity of 6/12 or better.
Able to understand and follow instructions for using the Airofit device.
Disqualifiers
a history of intraocular surgery,
a history of uveitis,
a spherical refractive error exceeding 3D,
a history of regular topical treatment other than artificial tears
Trial design
Design model
Single group
Treatments tested in this trial
Intraocular Pressure after forced expiration
Other interventionThe experiment will entail the acquisition of a total of seven intraocular pressure (IOP) measurements from each subject. * T0: Baseline (pre-intervention, resting). * T1: Immediately after 1 minute of forced expiration at Level 1. * T2: Immediately after 1 minute of forced expiration at Level 2. * T3: Immediately after 1 minute of forced expiration at Level 3. * T4: Immediately after 1 minute of forced expiration at Level 4. * T5: Immediately after 1 minute of forced expiration at Level 5. * T6: Immediately after 1 minute of forced expiration at Level 6.
Treatment groups
60 Participants
are divided into 1 treatment groupGroup A: Forced expiration programExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Intraocular Pressure Measurement
The intraocular pressure will be measured in both eyes using a calibrated Tonoref III non-contact tonometry (Nidek Co., Ltd., Gamagori, Aichi, Japan) and applanation tonometry (A900 tonometer, Costruzione Strumenti Oftalmici, Firenze, Italy) by a single examiner
Time frame
T0: Baseline / T1: after 1 minute of forced expiration at Level 1 /T2: after 1 minute of forced expiration at Level 2/T3: Immediately after 1 minute of forced expiration at Level 3Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov