The Effect of IPD on Lateral Bone Augmentation

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorQueen Mary University of London

About this trial

Guided Bone Regeneration (GBR) is a widely used technique during dental implant surgery to help rebuild bone around the implant and improve its long-term appearance and stability. This study investigates whether the amount of bone that regrows depends on a person's original bone shape, known as the Individual Phenotypical Dimension (IPD). The aim is to compare the bone stability and overall results between two approaches: adding bone only up to the original bone line (IPD) or adding bone beyond it (over-contour augmentation). Over the course of a year, the study will assess not only bone and soft tissue healing, but also gum blood flow, implant success, and patient satisfaction.

There will be two treatment groups in this study - one group will receive bone grafting just up to their natural bone shape, while the other group will receive a slightly larger graft that extends about 3 mm beyond it. Throughout the study CBCT scans will be taken to assess bone changes around the implant area in order to measure how the bone shape and thickness change over time after surgery.

Eligibility criteria

Qualifiers

Adult (>18 years old) patients

Good medical and psychological health

Engaged patients presenting with a Full Mouth Plaque Score (FMPS) of ≤ 20% within the 6 weeks prior to enrolment

Need of a tooth/teeth replacement in the incisor, canine or premolar maxillary region that could be provided with an implant-supported fixed prosthesis

Disqualifiers

Any known systemic disease severely affecting bone metabolism (e.g., Cushing's syndrome, Crohn's disease, rheumatoid arthritis, osteoporosis or diabetes type I and uncontrolled diabetes type II).

Self-reported HIV or other severe immunosuppression.

Self-reported alcoholism or chronic drug abuse.

Heavy smokers ( > 10 cigarettes/day)

Trial design

Treatments tested in this trial

  • Group 1 (Test Group): IP and GBR as an over-contour augmentation beyond IPD
  • Group 2 (Control Group): IP and GBR as a contour augmentation up to IPD

Treatment groups

28 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Queen Mary University of London

Lead sponsor

University of Belgrade

Collaborator