[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100462214":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":23,"centralContacts":28,"locations":33,"responsibleParty":51,"collaborators":22,"id":53,"slug":22,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":22,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":22,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":73,"overallStatus":35,"whyStopped":22,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Case Western Reserve University","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"Ambient noise followed by Womb sound","At 34 weeks corrected age, preterm infants (29-33 weeks gestational age at birth), who are off respiratory support \\>1.5 lpm, will be exposed to alternating 6-hour periods of a recording of ambient noise followed by commercially available womb sounds over a 24-hour period for a combined total of 12 hours of womb sounds and 12 hours of ambient noise.",[12],"Other: Womb sound recordings",{"label":14,"type":6,"description":15,"interventionNames":16},"Womb sound recordings followed by ambient noise","At 34 weeks corrected age, preterm infants (29-33 weeks gestational age at birth), who are off respiratory support \\>1.5 lpm, will be exposed to alternating 6-hour periods of a recording of commercially available womb sounds followed by ambient noise over a 24-hour period for a combined total of 12 hours of womb sounds and 12 hours of ambient noise.",[12],[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"Womb sound recordings","Womb sounds will be chosen from commercially available (Amazon) womb recordings using a recording that most closely resembles the womb including maternal heart rate, fetal heartbeat, respiratory sounds, bowel \"popping\" sounds and frequency spectra as described by Parga, Daland 2018 et al.",[9,14],null,[24],{"name":25,"affiliation":26,"role":27},"Cynthia Bearer, MD","University Hospitals Cleveland Medical Center","PRINCIPAL_INVESTIGATOR",[29],{"name":25,"role":30,"phone":31,"phoneExt":22,"email":32},"CONTACT","216 844-3387","Cynthia.Bearer@UHhospitals.org",[34],{"facility":26,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Cleveland","Ohio","44106-7061","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-81.69541,41.4995,{"lat":45,"lon":44},[48,50],{"name":49,"role":30,"phone":22,"phoneExt":22,"email":22},"Associate Chief Scientific Officer",{"name":25,"role":27,"phone":22,"phoneExt":22,"email":22},{"type":52,"investigatorFullName":22,"investigatorTitle":22,"investigatorAffiliation":22,"oldNameTitle":22,"oldOrganization":22},"SPONSOR","100462214",false,"NCT05298748","The Effect of Womb Recordings on Maturation of Respiratory Control in Preterm Infants","Womb Recordings and Respiratory Control Maturation in Neonates","Inclusion Criteria:\n\n* preterm infants 29-33 weeks gestational age at birth\n* 34 weeks corrected age\n* off respiratory support \\>1.5 lpm\n\nExclusion Criteria:\n\n* on respiratory support \\>1.5 lpm\n* congenital anomalies","ALL","1 Week","5 Weeks",{"count":63,"type":64},34,"ESTIMATED","INTERVENTIONAL",[67],"NA","The aim of this proposal is to characterize the acute effect of early postnatal sound exposure on neuronal maturation of the respiratory control regions of the brain in preterm infants.",[70,71,72],"Apnea of Prematurity","Intermittent Hypoxemia","Bradycardia",[74],"apnea, intermittent hypoxemia, bradycardia, audio recording","2025-12-04",{"date":77,"type":78},"2025-12-05","ACTUAL",{"date":80,"type":78},"2022-09-16",{"date":82,"type":64},"2026-11",{"name":5,"class":6},1]