The aim of this study is to evaluate the effects of a specialized oral nutritional supplement (SF) enriched with BCAAs, omega-3 fatty acids, and dietary fiber on improving the nutritional status of dialysis patients with mild to moderate malnutrition, and thereby alleviating fatigue and enhancing quality of life. We will assess various aspects of protein-energy wasting (PEW), as well as changes in the Malnutrition Inflammation Score (MIS), Geriatric Nutritional Risk Index (GNRI), fatigue, appetite, serum BCAA levels, uremic toxins, and gut microbiota composition.
Patients with ESRD who have been receiving dialysis for more than three months
Serum albumin (Alb) ≤ 4.0 g/dL, or body mass index (BMI) ≤ 20, or normalized protein catabolic rate (nPCR) ≤ 0.8
Male or female patients aged 20 years or older
Serum albumin (Alb) < 3.0 g/dL
Known allergy or intolerance to any component of the product, or deemed by a physician to be unable to complete the trial
Patients who refuse to sign the informed consent form or are unable to follow study instructions
Pregnant or breastfeeding women
Buddhist Tzu Chi General Hospital
Lead sponsor
Multipower Enterprise Corp.
Collaborator