[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100308735":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":56,"centralContacts":61,"locations":68,"responsibleParty":86,"collaborators":10,"id":88,"slug":10,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":10,"eligibilityCriteria":93,"healthyVolunteers":94,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":10,"studyType":101,"phases":10,"briefSummary":102,"conditions":103,"keywords":10,"overallStatus":71,"whyStopped":10,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":116},{"fullName":5,"class":6},"University Ghent","OTHER",[8,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Natural cycle",null,"15 female volunteers, not using hormonal contraception, will be scanned during 3 menstrual cycles. During each cycle, the volunteers will be scanned 3 times: during the follicular phase, during ovulation and during luteal phase.",[13,14,15,16,17,18,19],"Device: MRI scan","Device: Physiological monitoring","Biological: Blood sample","Device: Blood pressure measurement","Device: Body temperature","Other: Questionnaires","Diagnostic Test: Pregnancy test",{"label":21,"type":10,"description":22,"interventionNames":23},"Anti-conception","15 female volunteers, using hormonal contraception pill Deso 20, will be scanned during 3 menstrual cycles. During each cycle, the volunteers will be scanned 2 times: during the pill-week and during the pill-free week.",[13,14,15,16,17,18],[25,30,34,39,43,47,51],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"DEVICE","MRI scan","Several MRI scan modalities: MPRAGE (structural scan), arterial spin labeling (cerebral perfusion), resting state functional-MRI (fMRI, cerebral activity) and diffusion MRI (white matter diffusion and white matter tracts).",[21,9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"Physiological monitoring","During MRI: heart rate, end-tidal carbon dioxide (CO2), respiratory rate and skin conductance",[21,9],{"type":35,"name":36,"description":37,"armGroupLabels":38,"otherNames":10},"BIOLOGICAL","Blood sample","Blood sample after MRI-session: measurement of hematocrit, hemoglobin, estradiol, progesterone, follicle stimulation hormone and luteinizing hormone.",[21,9],{"type":26,"name":40,"description":41,"armGroupLabels":42,"otherNames":10},"Blood pressure measurement","Measuring blood pressure before and after MRI-scan",[21,9],{"type":26,"name":44,"description":45,"armGroupLabels":46,"otherNames":10},"Body temperature","Measuring body temperature before and after MRI-scan",[21,9],{"type":6,"name":48,"description":49,"armGroupLabels":50,"otherNames":10},"Questionnaires","Questionnaires at the start of the study on lifestyle. Additionally, a questionnaire before each scan session on the actual state of the volunteer (e.g. mood, caffeine consumption, alcohol, medication, etc.)",[21,9],{"type":52,"name":53,"description":54,"armGroupLabels":55,"otherNames":10},"DIAGNOSTIC_TEST","Pregnancy test","Test for pregnancy using a pregnancy dipstick test",[9],[57],{"name":58,"affiliation":59,"role":60},"Eric Achten, MD, PhD","University Hospital, Ghent","PRINCIPAL_INVESTIGATOR",[62],{"name":63,"role":64,"phone":65,"phoneExt":66,"email":67},"Patricia Clement, Msc","CONTACT","9 332 1330","+32","patricia.clement@ugent.be",[69],{"facility":70,"status":71,"city":72,"state":10,"zip":73,"country":74,"countryCode":75,"cosmosGeoPoint":76,"geoPoint":81,"contacts":82},"Ghent University Hospital","RECRUITING","Ghent","9000","Belgium","BE",{"type":77,"coordinates":78},"Point",[79,80],3.71667,51.05,{"lat":80,"lon":79},[83],{"name":84,"role":64,"phone":85,"phoneExt":66,"email":67},"Patricia Clement, MSc","477566590",{"type":87,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100308735",false,"NCT03299179","The Effects of the Female Hormones on Cerebral Perfusion","The Effects of the Female Sex Hormones and Hormonal Contraception on Cerebral Perfusion","Inclusion Criteria:\n\n* Bachelor or Master student\n* Minimum of 3 months not using contraception of using Deso20\n\nExclusion Criteria:\n\n* No informed consent\n* MRI-contraindications\n* Claustrophobia\n* Pregnancy or breastfeeding\n* Chronic diseases and chronic medication use\n* Smoker\n* Drug use\n* Abuse of alcohol and caffeine",true,"FEMALE","18 Years","25 Years",{"count":99,"type":100},62,"ESTIMATED","OBSERVATIONAL","Measuring brain perfusion is biased by a inter- and intrasubject variability, caused by physiological and lifestyle factors. In this study, the investigators want to investigate the variations in cerebral perfusion and other brain parameters (grey matter, resting-state brain activity, brain connectivity and white matter diffusion) caused by the female sex hormones and hormonal contraception.",[104,105,106],"Cerebral Perfusion","Contraception","Menstrual Cycle","2023-12-05",{"date":109,"type":110},"2023-12-06","ACTUAL",{"date":112,"type":110},"2016-10-03",{"date":114,"type":100},"2027-12-31",{"name":5,"class":6},1]