The Impact of Blood Pressure Variability During the Induction and Surgical Periods on Postoperative Acute Kidney Injury

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorZhongda Hospital

About this trial

The goal of this multicenter retrospective cohort study aimed to explore the effect of BPV during anesthesia induction and surgery on the occurrence of postoperative AKI in non-cardiac surgery patients.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Undergoing non-cardiac surgery;

Adult;

Disqualifiers

Undergoing urological surgeries that partially directly affect kidney function (including relief of urinary tract obstruction, nephrectomy, or kidney transplantation);

Surgery duration less than 60 minutes;

Weight < 30 kg or BMI > 35 kg/m2;

Patients who underwent reoperation within 7 days after surgery;

Trial population

Southeast University Zhongda Hospital (2013-2024), Nanjing First Hospital (2016-2024), and the First Affiliated Hospital of Anhui Medical University (2013-2023)

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

5,000 Participants
are grouped into 4 trial groups
Group A: HH
Group B: HL
Group C: LH
Group D: LL

Trial outcomes

Primary outcomes

1

AKI

AKI diagnosed according to KDIGO criteria within 7 days after surgery was the primary outcome event.

Time frame
Within 7 days after surgery.

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Zhongda Hospital

Lead sponsor

Nanjing First Hospital, Nanjing Medical University

Collaborator

The First Affiliated Hospital of Anhui Medical University

Collaborator

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