The Mediating Role of Balance in the Relationship Between Fatigue and Fear of Falling in Individuals With Multiple Sclerosis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-75
SponsorUskudar University

About this trial

Fatigue, balance impairment, and fear of falling are common problems in individuals with Multiple Sclerosis (MS). Previous studies have shown significant associations among these variables; however, the mechanisms underlying the relationship between fatigue and fear of falling remain unclear. It is possible that fatigue increases fear of falling indirectly through its negative effects on balance performance.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 18-65 years

Neurologist-confirmed MS diagnosis

No relapse within the previous 30 days

Ability to walk independently or with an assistive device

Disqualifiers

Recent MS relapse

Severe vestibular disorder

Other neurological diseases

Severe orthopedic conditions affecting mobility

Trial population

The study population will consist of adults diagnosed with multiple sclerosis who are clinically stable and able to complete the study assessments. Eligible participants will be recruited from the outpatient neurology and physical medicine and rehabilitation clinics of Başkent University.

Trial design

Design model

Other

Time perspective

Cross-sectional

Treatments tested in this trial

  • Observational Model: Cross-Sectional

    Other intervention

    Observational Model: Cross-Sectional

Treatment groups

40 Participants
are divided into 1 treatment group
Group A: Individuals with Multiple Sclerosis1 intervention

Trial outcomes

Primary outcomes

1

Falls Efficacy Scale-International

Fear of falling will be assessed using the Falls Efficacy Scale-International (FES-I). The FES-I is a 16-item questionnaire that evaluates concern about falling during a range of daily activities. Total scores range from 16 to 64, with higher scores indicating greater fear of falling.

Time frame
Time Frame: Baseline (single assessment)

Secondary outcomes

1

Fatigue Severity Scale (FSS)

Fatigue severity will be assessed using the Fatigue Severity Scale (FSS). The FSS consists of 9 items rated on a 7-point Likert scale. The total score is calculated as the mean of all items, with higher scores indicating greater fatigue severity.

Time frame
Baseline (single assessment)
2

Baseline (single assessment)

Balance performance will be evaluated using the Mini-Balance Evaluation Systems Test (Mini-BESTest). The Mini-BESTest consists of 14 items assessing dynamic balance. Total scores range from 0 to 28, with higher scores indicating better balance performance.

Time frame
Baseline (single assessment)

Other outcomes

Sponsors and contacts

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