[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645151":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":18,"locations":28,"responsibleParty":44,"collaborators":10,"id":46,"slug":10,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":10,"eligibilityCriteria":50,"healthyVolunteers":47,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":10,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":65,"whyStopped":10,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Uskudar University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Individuals with Multiple Sclerosis",null,"Adults diagnosed with multiple sclerosis who meet the eligibility criteria will participate in a single assessment session to evaluate fatigue, balance, and fear of falling.",[13],"Other: Observational Model: Cross-Sectional",[15],{"type":6,"name":16,"description":16,"armGroupLabels":17,"otherNames":10},"Observational Model: Cross-Sectional",[9],[19,24],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"osman çoban, phD","CONTACT","00905337242919","osman.coban@uskudar.edu.tr",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"günay çimen aysal, phd","00905336425822","gnycimen@gmail.com",[29],{"facility":30,"status":10,"city":31,"state":32,"zip":33,"country":34,"countryCode":10,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Üsküdar university","Istanbul","Üsküdar","34662","Turkey (Türkiye)",{"type":36,"coordinates":37},"Point",[38,39],28.94966,41.01384,{"lat":39,"lon":38},[42],{"name":43,"role":21,"phone":26,"phoneExt":10,"email":27},"Günay çimen aysal, phd",{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100645151",false,"NCT07680049","The Mediating Role of Balance in the Relationship Between Fatigue and Fear of Falling in Individuals With Multiple Sclerosis","Inclusion Criteria:\n\n* Age 18-65 years\n* Neurologist-confirmed MS diagnosis\n* No relapse within the previous 30 days\n* Ability to walk independently or with an assistive device\n* Ability to understand instructions\n* Voluntary participation\n\nExclusion Criteria:\n\n* Recent MS relapse\n* Severe vestibular disorder\n* Other neurological diseases\n* Severe orthopedic conditions affecting mobility\n* Recent lower extremity surgery or trauma\n* Cardiopulmonary conditions limiting assessment","ALL","18 Years","75 Years",{"count":55,"type":56},40,"ESTIMATED","OBSERVATIONAL","Fatigue, balance impairment, and fear of falling are common problems in individuals with Multiple Sclerosis (MS). Previous studies have shown significant associations among these variables; however, the mechanisms underlying the relationship between fatigue and fear of falling remain unclear. It is possible that fatigue increases fear of falling indirectly through its negative effects on balance performance.",[60],"Multiple Sclerosis",[62,60,63,64],"Fatigue","Postural Balance","Fear","NOT_YET_RECRUITING","2026-06-25",{"date":68,"type":69},"2026-07-01","ACTUAL",{"date":68,"type":56},{"date":72,"type":56},"2026-07-25",{"name":5,"class":6},1]