[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560088":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":10,"responsibleParty":18,"collaborators":10,"id":21,"slug":10,"hasResults":22,"nctId":23,"briefTitle":24,"officialTitle":25,"acronym":26,"eligibilityCriteria":27,"healthyVolunteers":22,"sex":28,"minAge":29,"maxAge":10,"enrollmentInfo":30,"targetDuration":10,"studyType":33,"phases":10,"briefSummary":34,"conditions":35,"keywords":37,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":10},{"fullName":5,"class":6},"First Affiliated Hospital, Sun Yat-Sen University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Adult-type diffuse gliomas",null,"Inclusion Criteria:\n\n1. First diagnosis of glioma, with no preoperative radiotherapy or chemotherapy.\n2. Underwent multiparametric MRI examination in our hospital before surgery.\n3. Tumor resection or biopsy was performed within 3 weeks after MRI examination.\n4. Pathological examination confirmed glioma.\n\nExclusion Criteria:\n\n1. Inability to cooperate during MRI examination, resulting in poor image quality that prevents image analysis.\n2. Surgery or biopsy specimens were unqualified and could not be analyzed pathologically.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Yingqian Huang","CONTACT","+86 17827066282","huangyq97@mail2.sysu.edu.cn",{"type":19,"investigatorFullName":14,"investigatorTitle":20,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ms.","100560088",false,"NCT06572592","The Predictive Value of MRI for Adult-type Diffuse Gliomas","The Prognostic Value of Preoperative Multi-model Diffusion MRI in Predicting Ki-67 Proliferation for Adult-type Diffuse Gliomas","MRI; glioma;","Inclusion Criteria:\n\n* First diagnosis of glioma, with no preoperative radiotherapy or chemotherapy.\n* Underwent multiparametric MRI examination in our hospital before surgery.\n* Tumor resection or biopsy was performed within 3 weeks after MRI examination.\n* Pathological examination confirmed glioma.\n\nExclusion Criteria:\n\n* Inability to cooperate during MRI examination, resulting in poor image quality that prevents image analysis.\n* Surgery or biopsy specimens were unqualified and could not be analyzed pathologically.","ALL","18 Years",{"count":31,"type":32},200,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the diagnostic value of preoperative MRI examination for adult-type diffuse gliomas. The main question it aims to answer is:\n\n* Can preoperative MRI examination noninvasively predict genotype of gliomas?\n* Can preoperative MRI examination noninvasively predict the overall survival of gliomas?\n* Can preoperative MRI examination noninvasively predict Ki-67 proliferation status?",[36],"Glioma",[38,39,40,41],"glioma","MRI","IDH","Ki-67","NOT_YET_RECRUITING","2024-08-25",{"date":45,"type":46},"2024-08-27","ACTUAL",{"date":48,"type":32},"2024-08-22",{"date":50,"type":32},"2030-05",{"name":5,"class":6}]