[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100596815":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":13,"locations":19,"responsibleParty":45,"collaborators":10,"id":49,"slug":10,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":10,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":67,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"The First Affiliated Hospital with Nanjing Medical University","OTHER",[8,11],{"label":9,"type":10,"description":10,"interventionNames":10},"pAVM with ruptured flow-related aneurysm",null,{"label":12,"type":10,"description":10,"interventionNames":10},"pAVM without ruptured flow-related aneurysm",[14],{"name":15,"role":16,"phone":17,"phoneExt":10,"email":18},"Yifei Wang","CONTACT","+86-13852665323","wangyifei5323@163.com",[20,34],{"facility":21,"status":22,"city":23,"state":24,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":10},"Jiangsu Province Hospital","ACTIVE_NOT_RECRUITING","Nanjing","Jiangsu","225500","China","CN",{"type":29,"coordinates":30},"Point",[31,32],118.77778,32.06167,{"lat":32,"lon":31},{"facility":35,"status":36,"city":23,"state":24,"zip":10,"country":26,"countryCode":27,"cosmosGeoPoint":37,"geoPoint":39,"contacts":40},"the First Affiliated Hospital of Nanjing Medical University","RECRUITING",{"type":29,"coordinates":38},[31,32],{"lat":32,"lon":31},[41],{"name":42,"role":16,"phone":43,"phoneExt":10,"email":44},"Hua Lu","+86-18761671021","luhua@njmu.cn",{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Lu Hua","professor","100596815",false,"NCT07050381","The Risk Factors Related to Rupture Flow-related Aneurysms in Posterior AVM","Risk Factors Related to Rupture Flow-related Aneurysms in Posterior Arteriovenious Malformation: A Muti-center Observentional Research.","pAVM-rFA","Inclusion Criteria:\n\n1. pAVM with flow-related aneurysms were identified by DSA, and subarachnoid hemorrhage was confirmed by CT\n2. No history of stroke, Marfan syndrome, polycystic kidney disease\n\nExclusion Criteria:\n\n1. pAVM without flow-related aneurysms\n2. Absence of clinical data","ALL",{"count":58,"type":59},200,"ESTIMATED","OBSERVATIONAL","AVMs have been reported to rupture at a formidable annual rate of 2% to 3% at natural progression, often resulting in longterm neurological deficits and poor functional outcomes.The reported risk of hemorrhagic presentation in patients with AVMs is 41% to 65%. While many studies suggest a correlation between higher hemorrhage risk and the concurrent presence of AVM and aneurysms, few authors have focused specifically on flow-related aneurysms alone. In many instances, the source of rupture is also unclear. Meta-analysis from 2016 suggested that 49.2% of hemorrhages were secondary to aneurysm rupture, 45% from AVM rupture, and 5.7% were undetermined.In a study of 302 patients, of which 52.6% had a hemorrhagic presentation, demonstrated a significant increase in rate of hemorrhage in those with flow-related aneurysms. Thus, it is necessary to figure out risk factors related to ruptured flow-related aneurysms in pAVM.",[63,64,65,66],"Arteriovenous Malformation of Central Nervous System","Aneurysm, Ruptured","Aneurysmatic Subarachnoid Haemorrhage","Aneurysm Cerebral",[68,69,70,71],"arteriovenous malformation","flow-related aneurysm","ruptured aneurysm","subarachnoid hemorrhage","2025-06-25",{"date":74,"type":75},"2025-07-03","ACTUAL",{"date":77,"type":75},"2025-06-13",{"date":79,"type":59},"2026-12-31",{"name":5,"class":6},2]