[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579276":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":19,"locations":11,"responsibleParty":25,"collaborators":11,"id":29,"slug":11,"hasResults":30,"nctId":31,"briefTitle":32,"officialTitle":33,"acronym":11,"eligibilityCriteria":34,"healthyVolunteers":30,"sex":35,"minAge":36,"maxAge":37,"enrollmentInfo":38,"targetDuration":11,"studyType":41,"phases":42,"briefSummary":44,"conditions":45,"keywords":11,"overallStatus":47,"whyStopped":11,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":11},{"fullName":5,"class":6},"Zhejiang Provincial People's Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"TI","EXPERIMENTAL",null,[13],"Device: temporally interfering electrical stimulation",[15],{"type":16,"name":17,"description":17,"armGroupLabels":18,"otherNames":11},"DEVICE","temporally interfering electrical stimulation",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":11,"email":24},"Li Zhang","CONTACT","+86-13732274598","zhangli0407@zju.edu.cn",{"type":26,"investigatorFullName":27,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Li Zhang, MD","Doctor","100579276",false,"NCT06822192","The Temporally Interfering in Patients with Disorders of Consciousness","The Efficacy and Safety of Temporally Interfering in Patients with Disorders of Consciousness","Inclusion Criteria:\n\nIn accordance with the international diagnostic criteria for MCS formulated by Giacino in 2002 or the diagnostic criteria for UWS proposed by Laureys in 2010; Patients with disease duration ≥28 days and unconscious improvement tendency in the past one month; No use of any sedative drugs or antiepileptic drugs (sodium or calcium channel blockers) in the past 1 month; stable vital signs; No obvious brain edema, hydrocephalus, and severe brain atrophy; Age from 18 to 70 years old; Informed consent was obtained from the patients' family members.\n\nExclusion Criteria:\n\nPrevious history of neurological or psychiatric disorders; Previous history of traumatic brain injury; History of cancer; Taking sedative drugs or antiepileptic drugs in the past 1 month; Unstable vital signs; Skull defect; The patients' family members did not sign the informed consent.","ALL","18 Years","75 Years",{"count":39,"type":40},40,"ESTIMATED","INTERVENTIONAL",[43],"NA","This project will help the patient recover consciousness by giving TI (temporally interfering) treatment",[46],"Disorders of Consciousness","NOT_YET_RECRUITING","2025-02-06",{"date":50,"type":51},"2025-02-12","ACTUAL",{"date":53,"type":40},"2025-02-20",{"date":55,"type":40},"2026-12-31",{"name":5,"class":6}]