[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100466247":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":22,"locations":33,"responsibleParty":50,"collaborators":18,"id":52,"slug":18,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":18,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":18,"overallStatus":75,"whyStopped":18,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Chronic Obstructive Pulmonary Disease Trial Network, Denmark","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Thermotherapy\u002Fsauna bath","EXPERIMENTAL","Must go to a sauna (min. Temperature 85℃) min. 4 times a week for 6 months. Each sauna bath must last at least 7 minutes. The intervention patients receive a subscription card for a sauna during the period. Patients will still receive pre-existing treatment",[13],"Other: Thermotherapy\u002Fsauna bath",{"label":15,"type":16,"description":17,"interventionNames":18},"No thermotherapy\u002Fsauna bath","NO_INTERVENTION","Not allowed to go to a sauna for 6 months. Patients who come to do so, by e.g. an oversight, however, remain in the study, to avoid introducing bias. It will be registered as a \"protocol violation\", but the patient will be included in Intention To Treat analysis and modified Intention To Treat analysis. Patients will still receive pre-existing treatment.",null,[20],{"type":6,"name":9,"description":9,"armGroupLabels":21,"otherNames":18},[9],[23,29],{"name":24,"role":25,"phone":26,"phoneExt":27,"email":28},"Josefin V Eklöf, MD","CONTACT","38673555","+45","josefin.viktoria.ekloef@regionh.dk",{"name":30,"role":25,"phone":31,"phoneExt":27,"email":32},"Jens-Ulrik S Jensen, Professor","38673057","jens.ulrik.jensen@regionh.dk",[34],{"facility":35,"status":18,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Herlev and Gentofte University hospital","Hellerup","Capital Region","2900","Denmark","DK",{"type":42,"coordinates":43},"Point",[44,45],12.57093,55.73204,{"lat":45,"lon":44},[48],{"name":49,"role":25,"phone":26,"phoneExt":27,"email":28},"josefin V Eklöf, MD",{"type":51,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100466247",false,"NCT05351242","THERMotherapy Against Persistent Bacterial LUNG Infections","Thermotherapy Against Persistent Bacterial LUNG Infections","THERMA-LUNG","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Competent and capable\n* FEV1\\>1,0 L\n* Have had a positive culture from sputum or BAL min. 2 times in the last 24 months for bacteria of the species: Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Staphylococcus aureus, Haemophilus influenzae, Achromobacter xylosoxidans, Klebsiella oxytoca or Klebsiella pneumoniae. In addition, min. 1 positive culture after treatment with antibiotics\n* Willing to go to a sauna (min. temperature of 85℃ for at least 7 minutes) four times weekly for six months or avoid going to a sauna for six months\n\nExclusion Criteria:\n\n* Allergy to lidocaine and\u002For midazolam\n* Contraindications to bronchoscopy\n* Previous severe laryngospasm (intubation requiring)\n* Pregnancy\u002Fbreastfeeding\n* Severe linguistic problems or inability to give informed consent\n* Severe mental illness that is not controlled with medication. NB: Patients with controlled mental illness can be included and will be asked on an equal footing as others","ALL","18 Years",{"count":62,"type":63},150,"ESTIMATED","INTERVENTIONAL",[66],"NA","The aim of this study is to determine whether an intervention with frequent thermotherapy will be able to reduce the amount of colonizing bacteria in the bronchoalveolar lavage sample and eradicate the colonizing bacteria.",[69,70,71,72,73,74],"Lung Diseases, Obstructive","Bronchiectasis","Asthma","Copd","Chronic Obstructive Pulmonary Disease","Chronic Lung Infections","NOT_YET_RECRUITING","2026-06-15",{"date":78,"type":79},"2026-06-17","ACTUAL",{"date":81,"type":63},"2026-10-01",{"date":83,"type":63},"2029-12-31",{"name":5,"class":6},1]