[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567215":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":12,"centralContacts":25,"locations":31,"responsibleParty":47,"collaborators":12,"id":51,"slug":12,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":22,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":12,"enrollmentInfo":59,"targetDuration":12,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":33,"whyStopped":12,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"Massachusetts General Hospital","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Usual Care","NO_INTERVENTION","Usual care at our institution involves a teaching visit with a nurse navigator and written handouts.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"THRIVE-CAR-T plus usual care","EXPERIMENTAL","Patients receiving the THRIVE-CAR-T intervention will receive usual care and will use the THRIVE-CAR-T digital application on an iPad when planned to receive CAR-T.",[18],"Behavioral: THRIVE-CAR-T",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"BEHAVIORAL","THRIVE-CAR-T","The intervention will begin several weeks prior to CAR-T cell therapy and will continue up until 30 days post CAR-T cell therapy. THRIVE-CAR-T is an educational and interactive digital application on an iPad for patients as they navigate receiving CAR-T. THRIVE-CAR-T is self-administered and provides education about the CAR-T cell therapy process, with several features to promote coping skills training informed by various well-established supportive psychotherapy strategies (e.g., cognitive behavior therapy, mindfulness, positive psychology), engagement, and health behavior change including gamification strategies, videos of patients who received CAR-T, and optional content.",[14],[26],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},"Patrick C Johnson, MD","CONTACT","6177244000","pcjohnson@mgh.harvard.edu",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"RECRUITING","Boston","Massachusetts","02114","United States","US",{"type":40,"coordinates":41},"Point",[42,43],-71.05977,42.35843,{"lat":43,"lon":42},[46],{"name":27,"role":28,"phone":29,"phoneExt":12,"email":30},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"SPONSOR_INVESTIGATOR","Patrick C. Johnson, MD","Assistant Professor of Medicine","100567215",false,"NCT06665295","THRIVE-CAR-T Digital App","Randomized Controlled Trial of a Supportive Care Digital Application (THRIVE-CAR-T) for Patients Receiving CAR-T Cell Therapy","Inclusion Criteria:\n\n1. Age 18 years or older\n2. Ability to understand English\n3. Diagnosis of a hematologic malignancy\n4. Receiving autologous CAR-T at MGH with an FDA approved cellular therapy product\n\nExclusion Criteria:\n\n1. Impaired cognition or uncontrolled mental illness that prohibits the ability to provide informed consent based on the oncology clinician assessment\n2. Already participating in another supportive care clinical trial","ALL","18 Years",{"count":60,"type":61},100,"ESTIMATED","INTERVENTIONAL",[64],"NA","The goal of this clinical trial is to learn if a digital mobile application called THRIVE-CAR-T is helpful for the care of patients undergoing CAR-T cell therapy. The main question\\[s\\] it aims to answer are whether the THRIVE-CAR-T app is feasible and acceptable to patients.",[67],"CAR T-Cell Therapy",[69,70,71,72],"car-t cell therapy","digital application","mobile application","randomized controlled trial","2026-03-26",{"date":75,"type":76},"2026-04-01","ACTUAL",{"date":78,"type":76},"2024-10-17",{"date":80,"type":61},"2026-12-31",{"name":49,"class":6},1]