[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588013":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":31,"responsibleParty":55,"collaborators":10,"id":57,"slug":10,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":10,"eligibilityCriteria":62,"healthyVolunteers":58,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Prospective Arm",null,"Children, young adolescents younger than 15 years, and young adults (15 to 39 years) with histologically confirmed patients with skeletal or extra-skeletal OS or ES with localized or metastatic disease stages.",[13],"Diagnostic Test: KLF factor (4 and 7)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","KLF factor (4 and 7)","Immunohistochemical staining of 4 um sections prepared from paraffin blocks using KLF factor (4 and 7) by automated immunostaining using the streptavidin-biotin technique.",[9],[21],{"name":22,"affiliation":23,"role":24},"Fatma S E Ebeid","Faculty of Medicine Ain Shams University","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Fatma S E Ebeid, MD","CONTACT","01095569596","fatmaebeid@med.asu.edu.eg",[32,47],{"facility":5,"status":33,"city":34,"state":10,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Cairo","11566","Egypt","EG",{"type":39,"coordinates":40},"Point",[41,42],31.24967,30.06263,{"lat":42,"lon":41},[45],{"name":46,"role":28,"phone":29,"phoneExt":10,"email":30},"Fatma Ebeid",{"facility":48,"status":33,"city":34,"state":10,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":49,"geoPoint":51,"contacts":52},"Faculty of Medicine Ain Shams Research Institute- Clinical Research Center (MASRI-CRC)",{"type":39,"coordinates":50},[41,42],{"lat":42,"lon":41},[53,54],{"name":46,"role":28,"phone":29,"phoneExt":10,"email":30},{"name":46,"role":24,"phone":10,"phoneExt":10,"email":10},{"type":56,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100588013",false,"NCT06935864","Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors","The Prognostic Value of Tissue Expression of Krüppel-Like Factors 4 and 7 in Bone Tumors","Inclusion Criteria:\n\nAge: children, young adolescents younger than 15 years, and young adults (15 to 39 years) Gender: Males and female. Histologically confirmed patients with skeletal or extra-skeletal OS or ES. Both localized and metastatic disease stages.\n\nExclusion Criteria:\n\nPatients with second malignant bone sarcoma. Patients with benign bone tumors.","ALL","1 Month","39 Years",{"count":67,"type":68},30,"ESTIMATED","OBSERVATIONAL","The current study is to assess the prognostic value of Krüppel-like factors 4 and 7 in bone tumors, and its role in the disease progression.",[72,73],"Osteosarcoma in Children","Ewing Sarcoma of Bone or Soft Tissue",[75,76,77],"Bone Tumor","Osteosarcoma","Ewing sarcoma","2025-04-12",{"date":80,"type":81},"2025-04-20","ACTUAL",{"date":83,"type":81},"2024-08-16",{"date":85,"type":68},"2026-02",{"name":5,"class":6},2]