[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100577525":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":30,"locations":40,"responsibleParty":71,"collaborators":25,"id":74,"slug":25,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":25,"eligibilityCriteria":78,"healthyVolunteers":75,"sex":79,"minAge":80,"maxAge":25,"enrollmentInfo":81,"targetDuration":25,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of South Carolina","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"In-Person Group","EXPERIMENTAL","For the supervised in-person group, all activities will be performed at the Train Your Brain Fitness Center in Columbia, SC. Participants will have real-time coaching and feedback from study coaches for each of the twice weekly exercise (up to 120 minutes weekly).Coaches will record exercises and intensity.",[13],"Behavioral: Supervised Exercise and Behavior Modification Support",{"label":15,"type":10,"description":16,"interventionNames":17},"Distance Group","For the monitored distance group, all activities will be performed at a fitness facility near their home with prescribed plans provided by a study coach. These individuals will have support from a fitness facility personal trainer to complete the prescribed exercises for up to 7 visits in the first 12 weeks. They will perform the remaining twice weekly exercise (up to 120 minutes weekly) on their own and record the information in electronic or paper logs.",[18],"Behavioral: Monitored Exercise and Behavioral Modification Support",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Supervised Exercise and Behavior Modification Support","The exercise intervention will have a goal of up to minutes (60 minutes 2 x a week) of moderate intensity exercise building up to that amount based on ability. This will include 45-60 minutes per week of cardiovascular activity, 30-60 minutes of functional strength training targeting major muscle groups (to include at a minimum: a squat movement, an upper extremity push movement, an upper extremity pull movement, a carry movement, a stepping movement and a trunk stabilization movement), and 10-20 minutes of balance, agility and mobility exercises. Study coach is with the participant when they exercise and records exercise and intensity. Study coaches provide behavior modification support through goal setting, encouragement, feedback and reviewing outcomes.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Monitored Exercise and Behavioral Modification Support","The exercise intervention will have a goal of up to minutes (60 minutes 2 x a week) of moderate intensity exercise building up to that amount based on ability. This will include 45-60 minutes per week of cardiovascular activity, 30-60 minutes of functional strength training targeting major muscle groups (to include at a minimum: a squat movement, an upper extremity push movement, an upper extremity pull movement, a carry movement, a stepping movement and a trunk stabilization movement), and 10-20 minutes of balance, agility and mobility exercises. Support for performing their exercise will be provided by a personal trainer at the fitness facility where they exercise for up to seven visits. The remainder of the twice weekly exercise will be completed and logged by the participant on their own. Study coaches provide behavior modification support through goal setting, encouragement, feedback and reviewing outcomes via phone, text and\u002For email.",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Elizabeth Regan, PhD","CONTACT","7046092409","eregan@mailbox.sc.edu",{"name":37,"role":33,"phone":38,"phoneExt":25,"email":39},"Amberly Osteen","(803) 216-3896","Amberly.osteen@uscmed.sc.edu",[41,58],{"facility":42,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Arnold School of Public Health","RECRUITING","Columbia","South Carolina","29208","United States","US",{"type":50,"coordinates":51},"Point",[52,53],-81.03481,34.00071,{"lat":53,"lon":52},[56],{"name":57,"role":33,"phone":34,"phoneExt":25,"email":35},"Elizabeth Regan",{"facility":59,"status":43,"city":60,"state":45,"zip":61,"country":47,"countryCode":48,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"Sumter YMCA","Sumter","29150",{"type":50,"coordinates":63},[64,65],-80.34147,33.92044,{"lat":65,"lon":64},[68],{"name":69,"role":33,"phone":70,"phoneExt":25,"email":35},"Elizabeth Regan, DPT, PhD","704-609-2409",{"type":72,"investigatorFullName":57,"investigatorTitle":73,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Clinical Associate Professor","100577525",false,"NCT06799429","Train Your Brain Fitness SC: An Exercise Intervention for People With Cognitive Impairments","Inclusion criteria:\n\n* adult (age \\>18)\n* medical diagnosis of mild-moderate cognitive impairment\n* medical clearance by referring provider for exercise\n* able to follow 2-step commands\n\nExclusion criteria:\n\n* significant pain with movement (\\>5\u002F10)\n* severe balance impairments or lack of independence on and off exercise equipment (by physical therapist judgment at Intake)","ALL","18 Years",{"count":82,"type":83},50,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this clinical trial is to test a twice a week, moderate intensity exercise and coaching program (an in-person group and a distance group) for adults with mild-moderate cognitive impairments living in South Carolina. The main questions it aims to answer are:\n\n1. Is the program practical to conduct, and it is acceptable and enjoyable? The hypothesis is that it will be possible to recruit participants, obtain the desired dosage of moderate intensity fitness and strength training twice a week for both groups.\n2. Are their changes at 3, 6, 9 and 12 months in endurance, mobility, cognitive function and perception of cognitive function? The hypotheses are that endurance, strength and mobility will improve and cognitive measures will not decline (remain the same or improve) for both groups.",[89],"Mild-moderate Cognitive Impairment",[91,92],"cognitive impairment","exercise","2026-05-27",{"date":95,"type":96},"2026-06-01","ACTUAL",{"date":98,"type":96},"2026-03-13",{"date":100,"type":83},"2026-11-17",{"name":5,"class":6},2]