[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597982":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":25,"id":53,"slug":25,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":54,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":73,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"The First Affiliated Hospital of Guangzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-intubated group","EXPERIMENTAL","Surgical procedure: non-intubated tracheal and carinal reconstruction",[13],"Procedure: non-intubated tracheal and carinal reconstruction",{"label":15,"type":16,"description":17,"interventionNames":18},"Intubated group","ACTIVE_COMPARATOR","Surgical procedure: intubated tracheal and carinal reconstruction",[19],"Procedure: intubated tracheal and carinal reconstruction",[21,26],{"type":22,"name":23,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","non-intubated tracheal and carinal reconstruction",[9],null,{"type":22,"name":27,"description":27,"armGroupLabels":28,"otherNames":25},"intubated tracheal and carinal reconstruction",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Shuben Li","CONTACT","86+(020) 8306 2114","13500030280@163.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":25},"the First Affiliated Hospital of Guangzhou Medical University","RECRUITING","Guangdong","Gaungzhou","510120","China","CN",{"type":45,"coordinates":46},"Point",[47,48],129.33635,42.76832,{"lat":48,"lon":47},{"type":51,"investigatorFullName":31,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Deputy Director","100597982",false,"NCT07065565","Tubeless Tracheal and Carinal Reconstruction","Non-intubated vs Intubated Anesthesia for Tracheal and Carinal Reconstruction","NOVA-01","Inclusion Criteria:\n\n1. Airway diseases were diagnosed by chest enhanced CT and bronchoscopy\n2. The patients with age ≥ 18 and ≤ 80 years old\n3. ASA (American Society of Anesthesiologists) stage: I-III\n4. sign the informed consent. -\n\nExclusion Criteria:\n\n1. The patients have proved history of congestive heart failure, angina without good control with medicine; ECG-proved penetrating myocardial infarction; hypertension with bad control; valvulopathy with clinical significance; arrhythmia with high risk and out of control\n2. The patients have severe systematic intercurrent disease, such as active infection or poorly controlled diabetes; coagulation disorders; hemorrhagic tendency or under treatment of thrombolysis or anticoagulant therapy\n3. Airway anatomical abnormalities due to a history of surgery\n4. Patients present with other malignancy","ALL","18 Years","80 Years",{"count":64,"type":65},176,"ESTIMATED","INTERVENTIONAL",[68],"NA","In recent year, non-intubated anesthesia had emerged as an available alternative for thoracic procedure. Whether non-intubated tracheal\u002Fcarinal reconstruction confers distinct perioperative advantages over the conventional intubated approach remains uncertain. The purpose of this study was to evaluate the safety and perioperative outcomes of non-intubated versus intubated approaches in tracheal and carinal reconstruction.",[71,72],"Tracheal Disease","Airway Disease",[74,75,76,77],"non-intubated anesthesia","airway disease","tracheal reconstruction","carinal reconstruction","2025-07-04",{"date":80,"type":81},"2025-07-15","ACTUAL",{"date":83,"type":81},"2025-03-26",{"date":85,"type":65},"2028-08-31",{"name":31,"class":6},1]