[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100597985":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":54,"id":56,"slug":25,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":78,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"The First Affiliated Hospital of Guangzhou Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-intubated group","EXPERIMENTAL","Patients received tubeless VATS for mediastinal neoplasm",[13],"Procedure: Non-intubated VATS for mediastinal neoplasm",{"label":15,"type":16,"description":17,"interventionNames":18},"Intubated group","ACTIVE_COMPARATOR","Patients received VATS mediastinal neoplasm resection under intubated general anesthesia.",[19],"Procedure: Intubated VATS for mediastinal neoplasm",[21,26],{"type":22,"name":23,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Non-intubated VATS for mediastinal neoplasm",[9],null,{"type":22,"name":27,"description":27,"armGroupLabels":28,"otherNames":25},"Intubated VATS for mediastinal neoplasm",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Shuben Li, Deputy Director","CONTACT","86(020) 8306 2114","13500030280@163.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":25},"the First Affiliated Hospital of Guangzhou Medical University","RECRUITING","Guangzhou","Guangdong","510120","China","CN",{"type":45,"coordinates":46},"Point",[47,48],113.25,23.11667,{"lat":48,"lon":47},{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Shuben Li","Deputy Director",[55],{"name":5,"class":6},"100597985",false,"NCT07065604","Tubeless VATS for Mediastinal Neoplasm","A Randomized Controlled Trial of Non-intubated Versus Intubated VATS for Mediastinal Neoplasm","NOVA-02","Inclusion Criteria:\n\n1. Mediastinal neoplasm was diagnosed by chest enhanced CT\n2. The patients with age ≥ 18 and ≤ 80 years old\n3. The patients whose tumor diameter was \\\u003C6 cm\n4. ASA grade: I-III\n5. The patients should understand the research and sign the informed consent\n\nExclusion Criteria:\n\n1. Imaging examinations revealed that the tumor had invaded adjacent organs, with evidence of pleural or pericardial dissemination, as well as lymphatic and\u002For hematogenous metastases\n2. Patients with a confirmed history of congestive heart failure, poorly controlled angina despite medical therapy, electrocardiogram-confirmed myocardial infarction with transmural involvement, uncontrolled hypertension, clinically significant valvular heart disease, or high-risk arrhythmias not adequately managed\n3. Patients with concurrent active malignancies","ALL","18 Years","80 Years",{"count":67,"type":68},132,"ESTIMATED","INTERVENTIONAL",[71],"NA","In recent year, non-intubated anesthesia had emerged as an available and promising alternative for thoracic procedure. However, its safety and feasibility in video-assisted thoracoscopic surgery (VATS) for mediastinal neoplasm remain controversial. This randomized controlled trial is designed to evaluate the impact of the non-intubated approach on surgical and perioperative outcomes in patients undergoing mediastinal neoplasm resection.",[74,75,76,77],"Mediastinal Neoplasm","VATS","Tubeless","Non-intubated Anesthesia",[77,76,74,75],"2025-07-04",{"date":81,"type":82},"2025-07-15","ACTUAL",{"date":84,"type":82},"2025-03-26",{"date":86,"type":68},"2028-08-31",{"name":52,"class":6},1]