[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100645203":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":60,"collaborators":10,"id":64,"slug":10,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":10,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":10,"enrollmentInfo":73,"targetDuration":10,"studyType":76,"phases":10,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":42,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Elazığ Mental Health and Diseases Hospital","OTHER_GOV",[8,12,15,18,21,23],{"label":9,"type":10,"description":11,"interventionNames":10},"Bipolar Disorder Type II (BD-II)",null,"Adult patients diagnosed with Bipolar Disorder Type II (BD-II) according to Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria. Patients with BD-II must have a history of at least one hypomanic episode and one major depressive episode and must be in remission at the time of study participation, with no current hypomanic, depressive, or mixed episode. Patients with active psychiatric disorders, a history of major psychiatric disorders, significant neurological disorders affecting cognitive functioning, or severe medical illnesses excluded\u002Fwill be excluded. Participants evaluated\u002Fwill be evaluated once in a cross-sectional assessment. No intervention assigned\u002Fwill be assigned by the study protocol. Assessments will include a sociodemographic data form, the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS).",{"label":13,"type":10,"description":14,"interventionNames":10},"Major Depressive Disorder (MDD)","Adult patients diagnosed with Major Depressive Disorder (MDD) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria. Patients with MDD must have a history of at least one major depressive episode and must be in remission at the time of study participation, with no current major depressive episode. Patients with a current or lifetime diagnosis of bipolar disorder, schizophrenia spectrum or other psychotic disorders, active psychiatric disorders requiring immediate treatment, significant neurological disorders affecting cognitive functioning, or severe medical illnesses excluded\u002Fwill be excluded. Participants evaluated\u002Fwill be evaluated once in a cross-sectional assessment. No intervention assigned\u002Fwill be assigned by the study protocol. Assessments will\u002Fincluded a sociodemographic data form, the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS).",{"label":16,"type":10,"description":17,"interventionNames":10},"Healthy Control (HC)","Healthy control (HC) adult participants without any current or past psychiatric disorder enrolled\u002Fwill be enrolled in the study. No intervention was administered\u002Fwill be administered as part of the research protocol. Participants undergo\u002Fwill undergo a baseline clinical evaluation. Clinical assessments in the HC group included\u002Fwill include the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS). Sociodemographic and clinical data was recorded\u002Fwill be recorded for all participants.",{"label":19,"type":10,"description":20,"interventionNames":10},"Healthy Father and\u002For Mother of Bipolar Disorder Type II (BD-II) Participant","Adult participants without any current or past psychiatric disorder enrolled\u002Fwill be enrolled in the study. No intervention was administered\u002Fwill be administered as part of the research protocol. Participants undergone\u002Fwill undergo a baseline clinical evaluation. Clinical assessments in the this group included\u002Fwill include the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS). Sociodemographic and clinical data was recorded\u002Fwill be recorded for all participants.",{"label":22,"type":10,"description":20,"interventionNames":10},"Healthy Father and\u002For Mother of Major Depressive Disorder (MDD) Participant",{"label":24,"type":10,"description":20,"interventionNames":10},"Healthy Father and\u002For Mother of Healthy Control (HC) Participant",[26],{"name":27,"affiliation":5,"role":28},"Mehmet Hamdi Örüm, Associate Professor, MD","STUDY_DIRECTOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":10,"email":34},"Mehmet Hamdi Örüm, MD, Associate Professor","CONTACT","+905382207558","mhorum@hotmail.com",{"name":36,"role":32,"phone":37,"phoneExt":10,"email":38},"Dilek Örüm, MD, Associate Professor","+905453681686","dr.dilekulukan@gmail.com",[40],{"facility":41,"status":42,"city":43,"state":10,"zip":44,"country":45,"countryCode":10,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Elazığ Fethi Sekin City Hospital","RECRUITING","Elâzığ","23200","Turkey (Türkiye)",{"type":47,"coordinates":48},"Point",[49,50],39.22321,38.67431,{"lat":50,"lon":49},[53,55,57],{"name":54,"role":32,"phone":37,"phoneExt":10,"email":38},"Dilek Örüm, MD Associate Professor",{"name":56,"role":32,"phone":33,"phoneExt":10,"email":34},"Mehmet Hamdi Örüm, MD Associate Professor",{"name":58,"role":59,"phone":10,"phoneExt":10,"email":10},"Dilek Örüm, Associate Professor, MD","SUB_INVESTIGATOR",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mehmet Hamdi ÖRÜM","Associate Professor Mehmet Hamdi Örüm, MD, Psychiatrist","100645203",false,"NCT07679204","Type D Personality and Life Satisfaction in Bipolar Disorder Type 2 and Major Depressive Disorder","Examination of Type D Personality and Factors Associated With Life Satisfaction in Parents of Patients Diagnosed With Bipolar Disorder Type 2 and Major Depressive Disorder","1. For Bipolar Disorder Type II (BD-II) Group:\n\n   \\*Inclusion Criteria:\n   * Diagnosis of BD-II according to DSM-5-TR\n   * Remission period\n   * Age ≥ 18 years\n   * Provided informed consent\n\n   For Bipolar Disorder Type II (BD-II) Group:\n\n   \\*Exclusion Criteria:\n   * Hypertension\n   * Diabetes mellitus\n   * Chronic kidney disease\n   * Rheumatoid arthritis\n   * Systemic lupus erythematosus\n   * Cardiac illness\n   * Severe neurological disorders\n   * Immunological or systemic illness\n   * Primary psychiatric disorders other than BD-II and not in remission for BD-II\n   * Alcohol\u002Fdrug\u002Fsubstance use\n2. For Major Depressive Disorder (MDD) Group:\n\n   \\*Inclusion Criteria:\n   * Diagnosis of MDD according to DSM-5-TR\n   * Remission period\n   * Age ≥ 18 years\n   * Provided informed consent\n\n   For Major Depressive Disorder (MDD) Group:\n   * Exclusion Criteria:\n\n     * Hypertension\n     * Diabetes mellitus\n     * Chronic kidney disease\n     * Rheumatoid arthritis\n     * Systemic lupus erythematosus\n     * Cardiac illness\n     * Severe neurological disorders\n     * Immunological or systemic illness\n     * Primary psychiatric disorders other than MDD and not in remission for MDD\n     * Alcohol\u002Fdrug\u002Fsubstance use\n3. For Healthy Control (HC) Group:\n\n   \\*Inclusion Criteria:\n   * No psychiatric diagnosis\n   * No systemic or immunological illness\n   * Medication-free for at least one month\n   * Age ≥ 18 years\n   * Provided informed consent\n\n   For Healthy Control (HC) Group:\n\n   \\*Exclusion Criteria:\n   * Hypertension\n   * Diabetes mellitus\n   * Chronic kidney disease\n   * Rheumatoid arthritis\n   * Systemic lupus erythematosus\n   * Cardiac illness\n   * Severe neurological disorders\n   * Immunological or systemic illness\n   * Having psychiatric disorders\n   * Alcohol\u002Fdrug\u002Fsubstance use\n4. For Healthy Father and\u002For Mother of Bipolar Disorder Type II (BD-II) Group:\n\n   \\*Inclusion Criteria:\n   * No psychiatric diagnosis\n   * No systemic or immunological illness\n   * Medication-free for at least one month\n   * Age ≥ 18 years\n   * Provided informed consent\n\n   For Healthy Father and\u002For Mother of Bipolar Disorder Type II (BD-II) Group:\n\n   \\*Exclusion Criteria:\n\n   • Hypertension\n   * Diabetes mellitus\n   * Chronic kidney disease\n   * Rheumatoid arthritis\n   * Systemic lupus erythematosus\n   * Cardiac illness\n   * Severe neurological disorders\n   * Immunological or systemic illness\n   * Having psychiatric disorders\n   * Alcohol\u002Fdrug\u002Fsubstance use\n5. For Healthy Father and\u002For Mother of Major Depressive Disorder (MDD) Group:\n\n   \\*Inclusion Criteria:\n   * No psychiatric diagnosis\n   * No systemic or immunological illness\n   * Medication-free for at least one month\n   * Age ≥ 18 years\n   * Provided informed consent\n\n   For Healthy Father and\u002For Mother of Major Depressive Disorder (MDD) Group:\n\n   \\*Exclusion Criteria:\n\n   • Hypertension\n\n   • Diabetes mellitus\n\n   • Chronic kidney disease\n\n   • Rheumatoid arthritis\n\n   • Systemic lupus erythematosus\n\n   • Cardiac illness\n\n   • Severe neurological disorders\n   * Immunological or systemic illness\n   * Having psychiatric disorders\n   * Alcohol\u002Fdrug\u002Fsubstance use\n6. For Healthy Father and\u002For Mother of Healthy Control (HC) Group:\n\n   \\*Inclusion Criteria:\n\n   • No psychiatric diagnosis\n\n   • No systemic or immunological illness\n   * Medication-free for at least one month\n   * Age ≥ 18 years\n   * Provided informed consent\n\n   For Healthy Father and\u002For Mother of Healthy Control (HC) Group:\n\n   \\*Exclusion Criteria:\n   * Hypertension\n   * Diabetes mellitus\n   * Chronic kidney disease\n   * Rheumatoid arthritis\n   * Systemic lupus erythematosus\n   * Cardiac illness\n   * Severe neurological disorders\n   * Immunological or systemic illness\n   * Having psychiatric disorders\n   * Alcohol\u002Fdrug\u002Fsubstance use",true,"ALL","18 Years",{"count":74,"type":75},180,"ESTIMATED","OBSERVATIONAL","Bipolar Disorder Type II (BD-II) and Major Depressive Disorder (MDD) are common mood disorders associated with substantial psychological distress, impaired functioning, and reduced quality of life. BD-II is characterized by recurrent major depressive episodes and hypomanic episodes, whereas MDD is characterized by one or more major depressive episodes without a history of mania or hypomania. Both disorders have a significant genetic component, and family studies suggest that first-degree relatives may exhibit subclinical affective traits, personality characteristics, and psychosocial vulnerabilities related to these conditions. The aim of this cross-sectional study was to examine Type D personality traits and life satisfaction among patients with BD-II and MDD and parents of patients. The study recruited\u002Fwill recruit 30 patients with BD-II; 30 patients with MDD; 30 healthy control subjects; mothers and\u002For fathers of 30 healthy control subjects, mothers and\u002For fathers of 30 patients with BD-II, and mothers and\u002For fathers of 30 patients with MDD who are in remission and receiving follow-up care at the Psychiatry Outpatient Clinic of Elazığ Fethi Sekin City Hospital, Turkey (By Dilek ÖRÜM -Associate Professor of Psychiatry, dr.dilekulukan@gmail.com). Sociodemographic characteristics, Type D personality traits, general psychiatric symptoms, and life satisfaction assessed\u002Fwill be assessed using validated self-report measures, including the Type D Personality Scale (DS14), the Brief Psychiatric Rating Scale (BPRS), and the Adult Life Satisfaction Scale (ALSS).\n\nThe primary objective was\u002Fis to compare Type D personality characteristics and life satisfaction levels between patients with MDD and BD-II and between their parents. Secondary objectives included\u002Finclude investigating the associations between Type D personality traits, psychiatric symptom severity, and life satisfaction. The findings may contribute to a better understanding of familial psychological characteristics associated with mood disorders and may help identify potential psychosocial targets for preventive and supportive interventions among family members of affected individuals.",[79,13],"Bipolar Disorder II",[81,82,83,84],"Bipolar disorder type II","Major depressive disorder","Life satisfaction","Type D personality","2026-06-25",{"date":87,"type":88},"2026-07-01","ACTUAL",{"date":90,"type":88},"2024-12-23",{"date":92,"type":75},"2026-12-24",{"name":5,"class":6},1]