[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643145":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":39,"centralContacts":46,"locations":54,"responsibleParty":70,"collaborators":31,"id":72,"slug":31,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":31,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":105,"whyStopped":31,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"University of California, Los Angeles","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"Magnesium Glycinate","EXPERIMENTAL","Participants randomized to this arm will take blinded magnesium glycinate capsules nightly for 4 weeks. The current planning dose is approximately 240 mg elemental magnesium nightly, with final capsule count and label language based on the selected blinded formulation.",[13],"Dietary Supplement: Magnesium glycinate",{"label":15,"type":10,"description":16,"interventionNames":17},"Magnesium L-Threonate","Participants randomized to this arm will take blinded magnesium L-threonate capsules nightly for 4 weeks. The current planning target is approximately 2 g\u002Fday total magnesium L-threonate, with elemental magnesium content, capsule count, and label language confirmed before activation.",[18],"Dietary Supplement: Magnesium L-threonate",{"label":20,"type":21,"description":22,"interventionNames":23},"Placebo","PLACEBO_COMPARATOR","Participants randomized to this arm will take matching placebo capsules nightly for 4 weeks on the same blinded schedule.",[24],"Other: Placebo",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DIETARY_SUPPLEMENT","Magnesium glycinate","Blinded oral magnesium glycinate capsules taken nightly for 28 days.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Magnesium L-threonate","Blinded oral magnesium L-threonate capsules taken nightly for 28 days.",[15],{"type":6,"name":20,"description":37,"armGroupLabels":38,"otherNames":31},"Matching placebo capsules taken nightly for 28 days.",[20],[40,43],{"name":41,"affiliation":5,"role":42},"Jeremy Swisher, MD","PRINCIPAL_INVESTIGATOR",{"name":44,"affiliation":5,"role":45},"Joshua Goldman, MD","STUDY_DIRECTOR",[47,51],{"name":41,"role":48,"phone":49,"phoneExt":31,"email":50},"CONTACT","936-520-3595","jswisher@mednet.ucla.edu",{"name":52,"role":48,"phone":31,"phoneExt":31,"email":53},"Kimberly Burbank, MD","kburbank@mednet.ucla.edu",[55],{"facility":5,"status":31,"city":56,"state":57,"zip":58,"country":59,"countryCode":60,"cosmosGeoPoint":61,"geoPoint":66,"contacts":67},"Los Angeles","California","90095","United States","US",{"type":62,"coordinates":63},"Point",[64,65],-118.24368,34.05223,{"lat":65,"lon":64},[68,69],{"name":41,"role":48,"phone":49,"phoneExt":31,"email":50},{"name":52,"role":48,"phone":31,"phoneExt":31,"email":53},{"type":42,"investigatorFullName":41,"investigatorTitle":71,"investigatorAffiliation":5,"oldNameTitle":31,"oldOrganization":31},"Principal Investigator","100643145",false,"NCT07640685","UCLA Magnesium Formulation Athlete Study","Effects of Magnesium Glycinate and Magnesium L-Threonate on Sleep, Recovery, and Performance in Collegiate Athletes","Mg-Form","Inclusion Criteria:\n\n* Age 18 to 35 years.\n* Current UCLA varsity athlete.\n* Actively training or competing during the study period.\n* Willing to wear WHOOP or a study-approved wearable device continuously during baseline and treatment periods if wearable data are used.\n* Willing to take assigned study capsules nightly for 28 days.\n* Willing to complete brief daily REDCap surveys and weekly adherence\u002Fsafety check-ins.\n* Able to provide informed consent and comply with study procedures.\n\nExclusion Criteria:\n\n* Current magnesium supplementation without completion of an appropriate washout before baseline.\n* Current investigational drug or investigational supplement use.\n* Current use of prescription or over-the-counter sleep medications unless reviewed and permitted by the study clinician.\n* Diagnosed sleep disorder that, in the investigator's judgment, would confound outcomes or increase risk.\n* Significant kidney disease or another medical condition that may increase risk with magnesium supplementation.\n* Known intolerance or allergy to magnesium glycinate, magnesium L-threonate, placebo, or inactive study ingredients.\n* Use of medications with clinically relevant magnesium interactions unless reviewed and permitted by the study clinician.\n* Any other condition that, in the investigator's judgment, would make participation unsafe, compromise voluntary consent, or prevent valid outcome assessment.",true,"ALL","18 Years","35 Years",{"count":84,"type":85},150,"ESTIMATED","INTERVENTIONAL",[88],"NA","This randomized, double-blind, placebo-controlled trial will compare magnesium glycinate, magnesium L-threonate, and placebo in UCLA varsity athletes. Participants will complete a baseline monitoring period followed by 4 weeks of blinded nightly supplementation. WHOOP or study-approved wearable data will be used to evaluate sleep efficiency, total sleep time, sleep consistency, heart rate variability, resting heart rate, and recovery metrics. Baseline and final testing will assess selected reaction and physical performance outcomes. The primary outcome is change in WHOOP-derived sleep efficiency from baseline week to final treatment week.",[91,92,93],"Athletic Performance","Recovery","Sleep",[95,96,97,98,99,100,101,102,103,104],"magnesium glycinate","magnesium L-threonate","collegiate athletes","sleep duration","athlete recovery","WHOOP","heart rate variability","reaction time","placebo-controlled trial","dietary supplement","NOT_YET_RECRUITING","2026-06-05",{"date":108,"type":109},"2026-06-11","ACTUAL",{"date":111,"type":85},"2026-07",{"date":113,"type":85},"2027-06",{"name":5,"class":6},1]