[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568193":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":7,"responsibleParty":18,"collaborators":7,"id":22,"slug":7,"hasResults":23,"nctId":24,"briefTitle":25,"officialTitle":25,"acronym":7,"eligibilityCriteria":26,"healthyVolunteers":23,"sex":27,"minAge":28,"maxAge":7,"enrollmentInfo":29,"targetDuration":7,"studyType":32,"phases":7,"briefSummary":33,"conditions":34,"keywords":38,"overallStatus":42,"whyStopped":7,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":7},{"fullName":5,"class":6},"Assiut University","OTHER",null,[9,14],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Mona Zakria Hassab Elnabi, resident doctor","CONTACT","+201145682833","mony.zak05@gmail.com",{"name":15,"role":11,"phone":16,"phoneExt":7,"email":17},"Hend Mohamed Sayed, lecturer","01098988712","hend.m.saleh@gmail.com",{"type":19,"investigatorFullName":20,"investigatorTitle":21,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Mona Zakaria Hassab Elnabi Shahin","Resident doctor Principal investigator","100568193",false,"NCT06678035","Use of Simplified Lung Ultrasound Score for Predicting ICU Outcomes in Patients With Acute Respiratory Failure","Inclusion Criteria:\n\n* Age is or more than 18 years old.\n* Admission to ICU in the first24 hours at time of recruitment to the study.\n* Patients in respiratory failure \\[PaO2 is less then 60 % mmHg\\]\n\nExclusion Criteria:\n\n* Co- existing chronic lung disease, pathology of which is known display abnormalities on US examination (interstitial lung diseases, bronchiectasis).\n* Large pneumothorax or massive pleural effusion causing significant collapse and precluding proper visualization of underlying lung.\n* Conditions that may interfere with lung ultrasound quality or probe contact such as marked obesity, severe chest wall deformities, burns or wounds.","ALL","18 Days",{"count":30,"type":31},72,"ESTIMATED","OBSERVATIONAL","This study aims to\n\nPrimary Aims:\n\nVerify the predictability of the PLIS at admission in predicting major clinical outcomes including:\n\n* ICU mortality (or discharge) and time to death (or discharge)\n* Escalation of ventilatory support antibiotic therapy or supportive medications (inotropes, steroids, sedation, neuromuscular blockers).\n\nSecondary Aims:\n\n* Determine the correlation between initial PLIS and the degree of disease severity (as evaluated per SOFA and APACHE II scores)\n* Determine the correlation between initial PLIS and partial pressure of oxygen in arterial blood (PaO2) to Fraction of inspired oxygen (FiO2): PaO2\u002FFiO2\n* Explore the potential association between the type of ventilatory support, ventilatory settings and PLIS at different time points.\n* Verify whether the site of consolidation (anterior vs. posterior lung zones) can reliably predict mortality in in ALI patients.\n* Determine the correlation between the PLIS score and the degree of ALI as quantified by CT of the chest (whenever a CT study is available) at the time of admission.",[35,36,37],"Pneumnia","Chest Infection","Critically-ill Patients Admitted to the ICU for Acute Respitatory Failure, Regardless the Aetilogy",[39,40,41],"LUS","Acute respiratory failure","Critically-ill patients","NOT_YET_RECRUITING","2024-11-05",{"date":45,"type":46},"2024-11-07","ACTUAL",{"date":48,"type":31},"2024-11-20",{"date":50,"type":31},"2025-10-01",{"name":5,"class":6}]