[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641519":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":34,"collaborators":10,"id":36,"slug":10,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":37,"sex":41,"minAge":42,"maxAge":43,"enrollmentInfo":44,"targetDuration":10,"studyType":47,"phases":10,"briefSummary":48,"conditions":49,"keywords":10,"overallStatus":51,"whyStopped":10,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"TEE derived measurement vs direct catheter measurement",null,"Pediatric patients with isolated peri membranous VSD undergoing surgical closure will undergo intraoperative pressure gradient assessment using both TEE-derived and direct catheter-based measurements under general anesthesia",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"karim mohammad el kersh, MBBCH","CONTACT","01002123494","karim.elkersh@med.asu.edu.eg",[19],{"facility":20,"status":10,"city":21,"state":22,"zip":23,"country":24,"countryCode":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Ain Shams","Cairo","Abbasia","00202","Egypt","EG",{"type":27,"coordinates":28},"Point",[29,30],31.24967,30.06263,{"lat":30,"lon":29},[33],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"type":35,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100641519",false,"NCT07623330","Use of TEE Derived Measurement vs Direct Measurement Under General Anesthesia in Assessment of Pressure Gradient in Peri Membranous Ventricular Septal Defect","Inclusion Criteria:\n\n* Pediatric patients (6 months to 5 years).\n* Patients with isolated peri-membranous VSD.\n* Scheduled for surgical VSD closure.\n\nExclusion Criteria:\n\n* Refusal of legal guardians.\n* Patients with other types of VSD.\n* Patients with pulmonary vascular diseases.\n* Patients with unrestrictive VSD.\n* Recent or active upper respiratory tract infection.\n* Any relative or absolute contraindication for TEE.","ALL","6 Months","5 Years",{"count":45,"type":46},115,"ESTIMATED","OBSERVATIONAL","In this study, the investigators aim to compare the pressure gradient obtained by transesophageal echocardiography across the restrictive peri membranous VSD with direct catheter-based measurements of such gradient.",[50],"Peri Membranous Ventricular Septal Defect","NOT_YET_RECRUITING","2026-06-17",{"date":54,"type":55},"2026-06-22","ACTUAL",{"date":57,"type":46},"2026-05-27",{"date":59,"type":46},"2027-04-20",{"name":5,"class":6},1]