USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy

ConditionsPostoperative Pain Acute Cholecystitis Cholelithiasis Postoperative Nausea and Vomiting

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-65

SponsorHitit University

About this trial

Laparoscopic cholecystectomy (LC) can cause moderate-to-severe postoperative pain from visceral, referred shoulder, and incisional sources. Multimodal analgesia is recommended, but opioids carry significant side effects. Ultrasound-guided interfascial plane blocks offer a safe alternative. The Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) blocks T5-T12 dermatomes, while the Recto-Intercostal Fascial Plane Block (RIFPB) provides sensory blockade across the upper anterolateral abdomen. This study compares the postoperative analgesic efficacy of bilateral M-TAPA versus bilateral RIFPB in patients undergoing LC.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 18-65 years

ASA physical classification I-II

BMI < 35 kg/m²

Scheduled for elective laparoscopic cholecystectomy due to cholelithiasis

Disqualifiers

Refusal to participate in the study

BMI > 35 kg/m²

ASA physical classification III-V

Age < 18 or > 65 years

Trial design

Design model

Parallel

Treatments tested in this trial

M-TAPA Group
Procedure/Surgery
Patients receiving ultrasound-guided bilateral Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) using 20 ml of 0.25% bupivacaine per side, applied at the 10th rib level beneath the costochondral perichondrium after surgery while under anesthesia.
RIFPB Group
Procedure/Surgery
Patients receiving ultrasound-guided bilateral Recto-Intercostal Fascial Plane Block (RIFPB) using 20 ml of 0.25% bupivacaine per side, injected into the interfascial plane between the rectus abdominis muscle and the 6th-7th costal cartilages just below the xiphoid process, applied after surgery while under anesthesia.

Treatment groups

70 Participants

are divided into 2 treatment groups

Group A: M-TAPA GroupActive comparator 1 intervention

Group B: RIFPB GroupActive comparator 1 intervention

Trial outcomes

Primary outcomes

Postoperative Opioid Consumption

Total tramadol consumption (mg) via patient-controlled analgesia (PCA) recorded at 0-1, 1-12, 12-24 hours, and total 24 hours postoperatively.

Time frame

24 hours postoperatively

Sponsors and contacts

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Hitit University

Lead sponsor

Source ClinicalTrials.gov

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