Vagus Nerve Stimulation for Myelopathy
ConditionDegenerative Cervical Myelopathy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorWashington University School of Medicine
About this trial
The objective of this study is to generate preliminary data to establish the feasibility and effectiveness of transauricular vagus nerve stimulation (taVNS) to improve post-operative outcomes of moderate to severe degenerative cervical myelopathy (DCM)
Eligibility criteria
Qualifiers
18 years of age or older
Moderate or severe degenerative cervical myelopathy according to the mJOA
Decompression surgery planned
Disqualifiers
• Pregnancy
Electrically active implants (e.g. pacemaker)
Known diagnosis of amyotrophic lateral sclerosis, multiple sclerosis, rheumatoid arthritis, concomitant thoracic and/or lumbar stenosis, spine tumor, HIV-related myelopathy
Ongoing cancer therapy
Trial design
Treatments tested in this trial
- Vagus nerve stimulation (taVNS)
- Sham Stimulation
Treatment groups
36 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov