Velocity-Based Resistance Training in Kidney Transplant Recipients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorFundación Universitaria del Area Andina

About this trial

This randomized controlled trial aims to evaluate the effects of velocity-based resistance training on renal function and metabolic health in kidney transplant recipients. Participants will be randomized into two groups performing resistance training at different execution velocities (maximal intended vs. submaximal controlled). The intervention will last 12 weeks and include multi-joint exercises (squat, bench press, military press). Primary outcomes include renal function (serum creatinine, eGFR, blood urea nitrogen, uric acid) and metabolic markers (HDL, triglycerides, glucose, waist circumference, blood pressure). Secondary outcomes include muscle strength, force-velocity profile, anthropometry, physical activity, fitness perception, and adherence to immunosuppressive medication.

Eligibility criteria

Qualifiers

Men and women aged 18 to 50 years.

Kidney transplant performed ≥12 months before enrollment.

Stable graft function in the previous 6 months (serum creatinine < 1.5 mg/dL, no rejection episodes).

Written medical clearance from a nephrologist to perform moderate-to-vigorous physical activity.

Disqualifiers

Active autoimmune disorders.

Recent coronary disease (≤6 months).

Severe musculoskeletal limitations incompatible with resistance training.

Diagnosis of diabetes mellitus (pre- or post-transplant).

Trial design

Treatments tested in this trial

  • Velocity-Based Resistance Training - Submaximal Velocity Protocol
  • Velocity-Based Resistance Training - Maximal Velocity Protocol

Treatment groups

12 Participants
are divided into 2 treatment groups