[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546832":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":15,"centralContacts":20,"locations":25,"responsibleParty":42,"collaborators":7,"id":45,"slug":7,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":46,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":7,"studyType":58,"phases":7,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":28,"whyStopped":7,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"CentraCare","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":13},"DIAGNOSTIC_TEST","Poccl, Time constant, driving pressure","Ventilatory parameters",[14],"mechanical power",[16],{"name":17,"affiliation":18,"role":19},"Ramakanth Pata, MD FCCP","Centracare health System","PRINCIPAL_INVESTIGATOR",[21],{"name":17,"role":22,"phone":23,"phoneExt":7,"email":24},"CONTACT","320-240-2207","cookybrey1@gmail.com",[26],{"facility":27,"status":28,"city":29,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"St Cloud Hospital","RECRUITING","Saint Cloud","Minnesota","56303","United States","US",{"type":35,"coordinates":36},"Point",[37,38],-94.16249,45.5608,{"lat":38,"lon":37},[41],{"name":17,"role":22,"phone":23,"phoneExt":7,"email":24},{"type":19,"investigatorFullName":43,"investigatorTitle":44,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Ramakanth Pata","Principal Investigator","100546832",false,"NCT06400095","Ventilatory Parameters in Predicting Outcomes in ARDS Patients","Occlusion Pressure at 100 Msec, TCe ( Expiratory Time Constant ), Stress Energy Density, Mechanical Power, Ventilatory Ratio and C20\u002FCdyn in Predicting Outcomes in Patients With Moderately Severe ARDS, Who Are on Mechanical Ventilation","OCTANE","Inclusion Criteria:\n\n* Patients with Acute respiratory failure needing mechanical ventilation\n* Diagnosis of Severe ARDS with severity: PF ratio \\\u003C 150, with PEEP\u002FCPAP \\> 5\n\nExclusion Criteria:\n\n* r2 \\\u003C 0.95, monitored on the ventilator\n* Expiratory flow that is not first-order or non-exponential decay\n* Patients with Nor-epinephrine requirements \\> 0.1 mcg\u002Fkg\u002Fmin within 2 hours of intubation\n* Patients requiring ECMO ( Extracorporeal membrane oxygenation)\n* Patients with COPD or pulmonary fibrosis with a premorbid FEV1 \\\u003C 1.5 L\n* Severe atherosclerotic vascular disease\n* Patients with a chest tube, intra-abdominal hypertension or with its risk factors\n* Patients with structural heart disease including pulmonary hypertension (RVSP \\> 45) and heart failure\n* All comfort care orders in the ICU\n* Patients who underwent tracheostomy","ALL","19 Years","80 Years",{"count":56,"type":57},50,"ESTIMATED","OBSERVATIONAL","This is a single-centre prospective observational study aimed to determine if Pocc (occlusion pressure at 100 msec), TCe ( Expiratory time constant ), Mechanical Stress power, Ventilatory ratio and C20\u002FCdyn would predict outcomes in patients with moderately severe ARDS (Acute respiratory distress syndrome), who are on mechanical ventilation",[61,62],"ARDS","Mechanical Power",[64,65,66,67],"Expiratory time constant","Ventilator ratio","Cdyn\u002FC20","Occlusion pressure at 100 msec","2024-08-20",{"date":70,"type":71},"2024-08-22","ACTUAL",{"date":73,"type":71},"2023-06-01",{"date":75,"type":57},"2025-07",{"name":5,"class":6},1]